1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline

Base Information

Chemical Name:1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline
CAS No.:15832-21-0
Molecular Formula:C₂₀H₂₂N₂O₂
Molecular Weight:322.407
Hs Code.:
DSSTox Substance ID:DTXSID30935896
Mol file:15832-21-0.mol

Synonyms:BRN 0627948;15832-21-0;1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline;6,7-Dimethoxy-1-(indolyl-3-methyl)-1,2,3,4-tetrahydroisoquinoline;Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)-;5-23-13-00431 (Beilstein Handbook Reference);1-(1H-indol-3-ylmethyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline;DTXSID30935896;LS-85905;1-[(1H-Indol-3-yl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Suppliers and Price of 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline

Chemical Property:

Vapor Pressure:5.98E-11mmHg at 25°C
Boiling Point:520.9°Cat760mmHg
Flash Point:268.8°C
Density:1.189g/cm³
XLogP3:3.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:322.168127949
Heavy Atom Count:24
Complexity:418

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C2C(NCCC2=C1)CC3=CNC4=CC=CC=C43)OC

Technology Process of 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline

There total 5 articles about 1,2,3,4-Tetrahydro-6,7-dimethoxy-1-(1H-indol-3-ylmethyl)isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 13433-48-2
N-(2-(3,4-dimethoxyphenyl)ethyl)-2-(1H-indol-3-yl)acetamide

: 15832-21-0
1-((1H-indol-3-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With trichlorophosphate; In chloroform; for 3h; Heating;

Reference yield:

: 1-((1H-indol-3-yl)methyl)-6,7-dimethoxy-3,4-dihydroisoquinoline

: 15832-21-0
1-((1H-indol-3-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 - 20 ℃; for 10h;
DOI:10.1021/acs.jmedchem.6b01217

Reference yield:

: 87-51-4
indole-3-acetic acid

: 15832-21-0
1-((1H-indol-3-yl)methyl)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / 3 h / 170 °C

2: 90 percent / POCl₃ / CHCl₃ / 3 h / Heating

With trichlorophosphate; In chloroform;