Technology Process of 3-phenylcyclohex-2-en-1-amine hydrochloride (1:1)
There total 3 articles about 3-phenylcyclohex-2-en-1-amine hydrochloride (1:1) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 97 percent / sodium borohydride / methanol / 1.) 0 deg C, 30 min, 2.) room temperature, 1 h
2: 58 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 2.5 h / Ambient temperature
3: 1.) hydrazine hydrate, 2.) aq. HCl / 1.) methanol, reflux 2 h
With
hydrogenchloride; sodium tetrahydroborate; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm00403a013
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 58 percent / triphenylphosphine, diethyl azodicarboxylate / tetrahydrofuran / 2.5 h / Ambient temperature
2: 1.) hydrazine hydrate, 2.) aq. HCl / 1.) methanol, reflux 2 h
With
hydrogenchloride; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate;
In
tetrahydrofuran;
DOI:10.1021/jm00403a013
- Guidance literature:
-
With
hydrogenchloride; hydrazine hydrate;
Yield given. Multistep reaction;
1.) methanol, reflux 2 h;
DOI:10.1021/jm00403a013
