4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Base Information

Chemical Name:4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one
CAS No.:651778-63-1
Molecular Formula:C16H18INO2
Molecular Weight:383.229
Hs Code.:
DSSTox Substance ID:DTXSID20388418
Nikkaji Number:J2.037.818B
Wikidata:Q82183374
ChEMBL ID:CHEMBL233664

Synonyms:4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one;651778-63-1;CHEMBL233664;SCHEMBL6024349;DTXSID20388418;2(1H)-Pyridinone, 5-ethyl-3-iodo-6-methyl-4-(3,5-dimethylphenoxy)-;3-Iodo-4-(3,5-dimethylphenoxy)-5-ethyl-6-methyl-1,2-dihydropyridine-2-one

Suppliers and Price of 4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:383.03823
Heavy Atom Count:20
Complexity:457

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(NC(=O)C(=C1OC2=CC(=CC(=C2)C)C)I)C

Technology Process of 4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

There total 5 articles about 4-(3,5-dimethylphenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 121771-61-7
dichloro-3,5-dimethyliodobenzene

: 172469-75-9
5-ethyl-4-hydroxy-6-methylpyridin-2(1H)-one

: 651778-63-1
4-(3,5-dimethyl-phenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Guidance literature:: dichloro-3,5-dimethyliodobenzene; With sodium carbonate; at 20 ℃; for 0.5h;

5-ethyl-4-hydroxy-6-methylpyridin-2(1H)-one; With sodium carbonate; at 20 ℃; for 1h;
DOI:10.1016/j.bmcl.2006.10.082

Reference yield: 91.0%

: C₁₆H₁₈INO₂

: 651778-63-1
4-(3,5-dimethyl-phenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Guidance literature:: In N,N-dimethyl-formamide; Heating;
DOI:10.1016/j.bmcl.2003.09.045

Reference yield:

: 22445-41-6
3,5-dimethylphenyl iodide

: 651778-63-1
4-(3,5-dimethyl-phenoxy)-5-ethyl-3-iodo-6-methyl-1H-pyridin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: chlorine

2: aq. Na₂CO₃ / 20 °C

3: 91 percent / dimethylformamide / Heating

With chlorine; sodium carbonate; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2003.09.045