Chemical Property of 1-Iodo-3,5-dimethylbenzene
Chemical Property:
- Appearance/Colour:Clear light yellow liquid
- Vapor Pressure:0.103mmHg at 25°C
- Melting Point:-2.9°C (estimate)
- Refractive Index:n20/D 1.594(lit.)
- Boiling Point:229.9 °C at 760 mmHg
- Flash Point:99.3 °C
- PSA：0.00000
- Density:1.61 g/cm3
- LogP:2.90800
- Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
- Sensitive.:Light Sensitive
- Solubility.:Sparingly soluble (0.014 g/L) (25°C), Calc.
- XLogP3:3.7
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:0
- Rotatable Bond Count:0
- Exact Mass:231.97490
- Heavy Atom Count:9
- Complexity:80.6
- Purity/Quality:
-
99% *data from raw suppliers
1-Iodo-3,5-dimethylbenzene *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi, 
C
- Hazard Codes:Xi,C
- Statements:
36/37/38
- Safety Statements:
26-36-37/39
- MSDS Files:
-
SDS file from LookChem
Total 1 MSDS from other Authors
Useful:
- Canonical SMILES:CC1=CC(=CC(=C1)I)C
-
Uses
suzuki reaction 1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethyl aniline, an aryl amine, It is also used in the following studies; α-Arylation of ketones, Copper-catalyzed N-arylation of imidazoles, Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile, synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe2O4 catalyzed C-O cross-coupling with phenol, CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine, copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol. It is also employed as a starting material in the synthesis of biphenyl-3,3?,5,5?-tetracarboxylic acid, radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene. 1-Iodo-3,5-dimethylbenzene (5-iodo-m-xylene) is suitable for use in the synthesis of N-(3,5-xylyl)-N-ethylaniline, an arylamine.It may be used in the following studies:α-Arylation of ketones.Copper-catalyzed N-arylation of imidazoles.Cyanation of 5-iodo-m-xylene to form 3,5-dimethylbenzonitrile.Synthesis of 1,3-Dimethyl-5-phenoxybenzene by nano-CuFe2O4 catalyzed C-O cross-coupling with phenol.CuBr-catalyzed amination of 1-iodo-3,5-dimethylbenzene to form N-Allyl-3,5-dimethylbenzenamine.Copper-catalyzed C-S bond-formation between 5-iodo-m-xylene and thiophenol.As a starting material in the synthesis of biphenyl-3,3′,5,5′-tetracarboxylic acid.Radical bromination of 5-iodo-m-xylene by N-bromosuccinimide to form 1,3-bis(bromomethyl)-5-iodobenzene.
