2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride

Base Information

• Chemical Name: 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride
• CAS No.: 65178-90-7
• Molecular Formula: C17H14Cl2O3
• Molecular Weight: 337.202
• DSSTox Substance ID: DTXSID60597502
• Wikidata: Q82493057
• Mol file: 65178-90-7.mol

Synonyms:65178-90-7;2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride;2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoyl chloride;SCHEMBL822492;DTXSID60597502;JOHXGAFWXKHHFM-UHFFFAOYSA-N;2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionoyl chloride;2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionyl chloride;2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl chloride

Chemical Property of 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride

Chemical Property:

• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 336.0319997
• Heavy Atom Count: 22
• Complexity: 406

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C(=O)Cl)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl

Technology Process of 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride

There total 3 articles about 2-[4-(4-Chlorobenzoyl)phenoxy]-2-methylpropanoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.4%

fenofibric acid (42017-89-0) → 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropionyl chloride (65178-90-7)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃; for 3h;

Reference yield: 47.0%

→ 3-N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methylpropanoyl)-amino-1-nicotinoyl oxy-propane + 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropionyl chloride (65178-90-7)

Guidance literature:

Reference yield:

→ 2-[4-(4-chlorobenzoyl)-phenoxy]-2-methylpropionyl chloride (65178-90-7)

Guidance literature:

aus d. entspr. Carbonsaeure, SOCl2;

upstream raw materials:

fenofibric acid

Downstream raw materials:

N-2--2-methylpropionylurea

N-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoyl)diethanolamine

2-(4-(4-chlorobenzoyl)phenoxy)-2-methyl-N-(2H-tetrazol-5-yl)propanamide

2-(2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropanoyl)hydrazinecarboximidamide