2-(4-Methylphenyl)-1,8-naphthyridine

Base Information

Chemical Name:2-(4-Methylphenyl)-1,8-naphthyridine
CAS No.:65182-53-8
Molecular Formula:C15H12N2
Molecular Weight:220.274
Hs Code.:
DSSTox Substance ID:DTXSID90495128
Wikidata:Q82343077

Synonyms:2-(4-Methylphenyl)-1,8-naphthyridine;2-(p-Tolyl)-1,8-naphthyridine;65182-53-8;DTXSID90495128

Suppliers and Price of 2-(4-Methylphenyl)-1,8-naphthyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(4-Methylphenyl)-1,8-naphthyridine

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:220.100048391
Heavy Atom Count:17
Complexity:245

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC3=C(C=CC=N3)C=C2

Technology Process of 2-(4-Methylphenyl)-1,8-naphthyridine

There total 4 articles about 2-(4-Methylphenyl)-1,8-naphthyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 7521-41-7
2-Aminonicotinaldehyde

: 122-00-9
para-methylacetophenone

: 65182-53-8
2-(4'-methylphenyl)-1,8-naphthyridine

Guidance literature:: With potassium hydroxide; for 0.0666667h; microwave irradiation;

Reference yield:

: 536-50-5
CH₃C₆H₄CH(CH₃)OH

: 23612-57-9
(2-amino-3-pyridinyl)methanol

: 7-(p-tolyl)-1,2,3,4-tetrahydro-1,8-naphthyridine

: 65182-53-8
2-(4'-methylphenyl)-1,8-naphthyridine

Guidance literature:: With dodecacarbonyl-triangulo-triruthenium; potassium tert-butylate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tert-Amyl alcohol; at 130 ℃; for 1h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.5b01976