Tetrafluorophthalimide

Base Information

• Chemical Name: Tetrafluorophthalimide
• CAS No.: 652-11-9
• Molecular Formula: C8HF4NO2
• Molecular Weight: 219.095
• Hs Code.: 2925190090
• European Community (EC) Number: 667-801-0
• Nikkaji Number: J922.286C
• Mol file: 652-11-9.mol

Synonyms:Tetrafluorophthalimide;652-11-9;4,5,6,7-Tetrafluoroisoindoline-1,3-dione;4,5,6,7-tetrafluoroisoindole-1,3-dione;4,5,6,7-Tetrafluoro-1H-isoindole-1,3(2H)-dione;3,4,5,6-tetrafluorophthalimide;4,5,6,7-tetrafluoro-2,3-dihydro-1H-isoindole-1,3-dione;SCHEMBL1449417;MFCD00091519;AKOS024338243;SB64282;AS-33207;CS-0454608

Chemical Property of Tetrafluorophthalimide

Chemical Property:

• PSA: 49.66000
• LogP: 1.13700
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 0
• Exact Mass: 218.99434092
• Heavy Atom Count: 15
• Complexity: 294

Purity/Quality:

99% ^*data from raw suppliers

Tetrafluorophthalimide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C12=C(C(=C(C(=C1F)F)F)F)C(=O)NC2=O

Technology Process of Tetrafluorophthalimide

There total 6 articles about Tetrafluorophthalimide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

cyclohexylcarboxamide (1122-56-1) → 4,5,6,7-tetrafluorophthalimide (652-11-9) + Cyclohexanecarboxylic acid (98-89-5)

Guidance literature:

With 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione; at 140 ℃; for 144h;

DOI:10.1016/S0040-4039(00)82395-3

Reference yield: 77.0%

Benzeneacetamide (103-81-1) → phenylacetic acid (103-82-2) + 4,5,6,7-tetrafluorophthalimide (652-11-9)

Guidance literature:

With 4,5,6,7-tetrafluoroisobenzofuran-1,3-dione; at 145 ℃; for 120h;

DOI:10.1016/S0040-4039(00)82395-3

Reference yield: 70.0%

tert-butyl isocyanide (630-18-2) → 4,5,6,7-tetrafluorophthalimide (652-11-9) + Trimethylacetic acid (75-98-9)

Guidance literature:

With 3,4,5,6-tetrafluorophthalic acid; at 180 ℃; for 120h;

DOI:10.1016/S0040-4039(00)82395-3

upstream raw materials:

ethyl 4-cyanobenzoate

tert-butyl isocyanide

2,2-dimethylpropionamide

ethyl 5-cyanovalerate