DIETHYL (4-BIPHENYLYLMETHYL)PHOSPHONATE

Base Information

• Chemical Name: DIETHYL (4-BIPHENYLYLMETHYL)PHOSPHONATE
• CAS No.: 30818-70-3
• Molecular Formula: C17H21O3P
• Molecular Weight: 304.326
• Hs Code.: 2931900090
• Mol file: 30818-70-3.mol

Synonyms:diethyl biphenyl-4-ylmethylphosphonate;4-Phenylbenzyl-diethylphosphonat;diethyl 4-phenylbenzylphosphonate;

Chemical Property of DIETHYL (4-BIPHENYLYLMETHYL)PHOSPHONATE

Chemical Property:

• Vapor Pressure: 1.8E-07mmHg at 25°C
• Melting Point: 58-60oC
• Boiling Point: 438.3°Cat760mmHg
• Flash Point: 232.2°C
• PSA: 45.34000
• Density: 1.11g/cm³
• LogP: 5.11970

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL (4-BIPHENYLYLMETHYL)PHOSPHONATE

There total 10 articles about DIETHYL (4-BIPHENYLYLMETHYL)PHOSPHONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

p-phenylbenzyl bromide (2567-29-5) + triethyl phosphite (122-52-1) → diethyl (4-biphenylmethyl)phosphonate (30818-70-3)

Guidance literature:

at 100 - 150 ℃; for 26h; Inert atmosphere;

Reference yield: 97.0%

p-phenylbenzyl bromide (2567-29-5) + phosphonic acid diethyl ester (762-04-9) → diethyl (4-biphenylmethyl)phosphonate (30818-70-3)

Guidance literature:

phosphonic acid diethyl ester; With sodium hydride; In N,N-dimethyl-formamide; for 0.5h; Cooling with ice; Inert atmosphere;

p-phenylbenzyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 8.5h; Inert atmosphere;

DOI:10.1021/acs.joc.7b03148

Reference yield: 90.0%

biphenyl-4-methylchloride (1667-11-4) + triethyl phosphite (122-52-1) → diethyl (4-biphenylmethyl)phosphonate (30818-70-3)

Guidance literature:

at 140 - 150 ℃; for 24h;

DOI:10.1021/jo00005a018

upstream raw materials:

biphenyl-4-methylchloride

triethyl phosphite

p-phenylbenzyl bromide

biphenyl-4-yl methanol

Downstream raw materials:

trans-4,4'-diphenylstilbene

4-(4-(biphenyl-4-ylmethylene)cyclohexyloxy)-3-chlorobenzoic acid

methyl 4-(4-(biphenyl-4-ylmethylene)cyclohexyloxy)-3-chlorobenzoate

ethyl 4-(4-(biphenyl-4-ylmethylene)cyclohexyloxy)-3-chlorobenzoate

Refernces

• 1、 Hosseini-Sarvari, Mona,Koohgard, Mehdi. "Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine". . p. 5905 - 5911. Retrieved 2021/07/12.
• 2、 -. "Novel preparation method of sulfonium salt derivatives with stilbene as conjugated system". Paragraph 0101; 0102; 0104; 0109; 0110. . Retrieved 2018/09/21.