4-(Chloromethyl)biphenyl

Base Information

Chemical Name:4-(Chloromethyl)biphenyl
CAS No.:1667-11-4
Molecular Formula:C13H11Cl
Molecular Weight:202.683
Hs Code.:2903999090
European Community (EC) Number:216-786-5
NSC Number:16277
UNII:3F1186UU0M
DSSTox Substance ID:DTXSID6075190
Nikkaji Number:J142B
Wikidata:Q27257137
Mol file:1667-11-4.mol

Synonyms:4-(chloromethyl)biphenyl;4-chloromethylbiphenyl

Suppliers and Price of 4-(Chloromethyl)biphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Chloromethyl)biphenyl
50mg
$ 45.00

TRC
4-(Chloromethyl)biphenyl
500mg
$ 75.00

SynQuest Laboratories
4-(Chloromethyl)biphenyl
1 g
$ 16.00

SynQuest Laboratories
4-(Chloromethyl)biphenyl
5 g
$ 47.00

SynQuest Laboratories
4-(Chloromethyl)biphenyl
25 g
$ 109.00

Sigma-Aldrich
4-Phenylbenzyl chloride 98%
10g
$ 358.00

Sigma-Aldrich
4-Phenylbenzyl chloride 98%
1g
$ 100.00

Oakwood
4-Biphenylmethylchloride 98%
1g
$ 40.00

Matrix Scientific
4-Biphenylmethyl chloride 98%
5g
$ 42.00

Matrix Scientific
4-Biphenylmethyl chloride 98%
1g
$ 14.00

Total 69 raw suppliers

Chemical Property of 4-(Chloromethyl)biphenyl

Chemical Property:

Appearance/Colour:White ro Off-white crystalline powder
Vapor Pressure:0.000527mmHg at 25°C
Melting Point:70-73 °C
Refractive Index:1.578
Boiling Point:322.4 °C at 760 mmHg
Flash Point:143.2 °C
PSA：0.00000
Density:1.111 g/cm³
LogP:4.09240
XLogP3:4.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:2
Exact Mass:202.0549280
Heavy Atom Count:14
Complexity:153

Purity/Quality:

99% ^*data from raw suppliers

4-(Chloromethyl)biphenyl ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=C(C=C2)CCl
Uses 4-(Chloromethyl)biphenyl is an important biphenyl derivative, which has a wide range of applications in medicine, polymer liquid crystal and dyestuff. For example, it can be used to synthesize the non-steroidal anti-inflammatory drugs 4-biphenylacetic acid and fenbufen, and the anti-inflammatory and analgesic drug felbinacethyl.

Technology Process of 4-(Chloromethyl)biphenyl

There total 25 articles about 4-(Chloromethyl)biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 591-51-5
phenyllithium

: 589-17-3
p-bromobenzyl chloride

: 1667-11-4
biphenyl-4-methylchloride

Guidance literature:: p-bromobenzyl chloride; With bis(tri-t-butylphosphine)palladium⁽⁰⁾; oxygen; In toluene; at 20 ℃; for 0.0166667h; Schlenk technique;

phenyllithium; In toluene; at 0 ℃; for 0.0833333h; Schlenk technique;
DOI:10.1002/anie.201700417

Reference yield: 98.0%

: 191097-22-0
2-(2-tert-butyldimethylsiloxyethyl)-4H-benzo[1,4]oxazin-3-one

: 1667-11-4
biphenyl-4-methylchloride

Guidance literature:

Reference yield: 94.0%

: 644-08-6
4-Methylbiphenyl

: 1667-11-4
biphenyl-4-methylchloride

Guidance literature:: With N-chloro-succinimide; benzophenone; In acetonitrile; at 27 ℃; for 5h; regioselective reaction; Irradiation;
DOI:10.1016/j.tet.2017.05.008