1-Piperidinecarboxylic acid, 4-[[[1-[(2-furanylcarbonyl)amino]cyclohexyl]carbonyl]amino]-3-hydroxy-, 1,1-dimethylethyl ester

Base Information

• Chemical Name: 1-Piperidinecarboxylic acid, 4-[[[1-[(2-furanylcarbonyl)amino]cyclohexyl]carbonyl]amino]-3-hydroxy-, 1,1-dimethylethyl ester
• CAS No.: 652171-10-3
• Molecular Formula: C22H33N3O6
• Molecular Weight: 435.521
• Mol file: 652171-10-3.mol

Synonyms:

Chemical Property of 1-Piperidinecarboxylic acid, 4-[[[1-[(2-furanylcarbonyl)amino]cyclohexyl]carbonyl]amino]-3-hydroxy-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Piperidinecarboxylic acid, 4-[[[1-[(2-furanylcarbonyl)amino]cyclohexyl]carbonyl]amino]-3-hydroxy-, 1,1-dimethylethyl ester

There total 1 articles about 1-Piperidinecarboxylic acid, 4-[[[1-[(2-furanylcarbonyl)amino]cyclohexyl]carbonyl]amino]-3-hydroxy-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(furan-2-carboxamido)-cyclohexanecarboxylic acid (63203-41-8) + 4-amino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester (203503-03-1,1331777-74-2,443955-98-4) → 4-[N-[1-[N-(furan-2-ylcarbonyl)amino]cyclohexanecarbonyl]amino]-1-tert-butoxycarbonyl-3-piperidinol (652171-10-3)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃; for 4h;

Reference yield:

4-[N-[1-[N-(furan-2-ylcarbonyl)amino]cyclohexanecarbonyl]amino]-1-tert-butoxycarbonyl-3-piperidinol (652171-10-3) → 4-[N-[1-[N-(furan-2-ylcarbonyl)amino]cyclohexanecarbonyl]amino]-3-piperidinol hydrochloride

Guidance literature:

With hydrogenchloride; In ethyl acetate; at 20 ℃; for 2h;

upstream raw materials:

1-(furan-2-carboxamido)-cyclohexanecarboxylic acid

4-amino-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester