2-(2-methoxyphenyl)-1H-benzimidazole

Base Information

Chemical Name:2-(2-methoxyphenyl)-1H-benzimidazole
CAS No.:6528-85-4
Molecular Formula:C14H12N2O
Molecular Weight:224.262
Hs Code.:
European Community (EC) Number:804-298-0
DSSTox Substance ID:DTXSID10353953
Nikkaji Number:J641.508C
Wikidata:Q82131832
ChEMBL ID:CHEMBL209369
Mol file:6528-85-4.mol

Synonyms:2-(2-methoxyphenyl)-1H-benzimidazole;6528-85-4;2-(2-methoxyphenyl)-1H-benzo[d]imidazole;1H-Benzimidazole, 2-(2-methoxyphenyl)-;Oprea1_023878;Oprea1_281407;CHEMBL209369;SCHEMBL2096956;DTXSID10353953;OTAVA-BB 1325754;MFCD00447053;AKOS000635397;1h-benzo[d]imidazole,2-(2-methoxyphenyl)-;SR-01000311122;SR-01000311122-1

Suppliers and Price of 2-(2-methoxyphenyl)-1H-benzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-(2-Methoxyphenyl)-1H-benzimidazole
0.500g
$ 160.00

Alfa Aesar
2-(2-Methoxyphenyl)benzimidazole, 95%
1g
$ 228.00

Alfa Aesar
2-(2-Methoxyphenyl)benzimidazole, 95%
250mg
$ 73.50

Alfa Aesar
2-(2-Methoxyphenyl)benzimidazole, 95%
5g
$ 1003.00

AK Scientific
2-(2-Methoxyphenyl)-1H-benzimidazole
500mg
$ 266.00

Total 8 raw suppliers

Chemical Property of 2-(2-methoxyphenyl)-1H-benzimidazole

Chemical Property:

PSA：37.91000
LogP:3.23850
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:224.094963011
Heavy Atom Count:17
Complexity:259

Purity/Quality:

95% purity ^*data from raw suppliers

2-(2-Methoxyphenyl)-1H-benzimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=NC3=CC=CC=C3N2

Technology Process of 2-(2-methoxyphenyl)-1H-benzimidazole

There total 26 articles about 2-(2-methoxyphenyl)-1H-benzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 95-54-5
1,2-diamino-benzene

: 135-02-4
ortho-anisaldehyde

: 6528-85-4
2-(2-methoxyphenyl)benzimidazole

Guidance literature:: With N,N'-diiodo-N,N'-1,2-ethanediylbis(p-toluenesulphonamide); at 20 ℃; for 0.333333h; Neat (no solvent);
DOI:10.1002/cjoc.201090372

Reference yield: 93.2%

: 95-54-5
1,2-diamino-benzene

: 135-02-4
ortho-anisaldehyde

: 6528-85-4
2-(2-methoxyphenyl)benzimidazole

: 430435-76-0
1-(2-methoxybenzyl)-2-(-2-methoxyphenyl)-1H-benzimidazole

Guidance literature:: With silica gel supported trichloroacetic acid; In ethanol; water; at 50 ℃; for 0.2h; regioselective reaction; Sonication; Green chemistry;
DOI:10.1007/s12039-014-0662-4

Reference yield: 93.0%

: 95-54-5
1,2-diamino-benzene

: 21615-34-9
2-Methoxybenzoyl chloride

: 6528-85-4
2-(2-methoxyphenyl)benzimidazole

Guidance literature:: 1,2-diamino-benzene; 2-Methoxybenzoyl chloride; With triethylamine; In dichloromethane; at 0 ℃; for 3.5h;

With sodium acetate; acetic acid; for 19h; Heating / reflux;