4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester

Base Information

Chemical Name:4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester
CAS No.:653568-70-8
Molecular Formula:C15H17NO3S
Molecular Weight:291.371
Hs Code.:
DSSTox Substance ID:DTXSID50477001
Wikidata:Q82309019

Synonyms:653568-70-8;4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester;DTXSID50477001;AKOS019139701

Suppliers and Price of 4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:291.09291458
Heavy Atom Count:20
Complexity:306

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CSC(=N1)C2=CC=C(C=C2)COC

Technology Process of 4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester

There total 2 articles about 4-Thiazoleacetic acid, 2-[4-(methoxymethyl)phenyl]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 13176-46-0
4-bromoethyl acetoacetate

: 653568-68-4
4-methoxymethylbenzothioamide

: 653568-70-8
[2-(4-methoxymethyl-phenyl)-thiazol-4-yl]-acetic acid ethyl ester

Guidance literature:: In tetrahydrofuran; for 12h;

Reference yield:

: 1515-85-1
4-(methoxymethyl)benzonitrile

: 653568-70-8
[2-(4-methoxymethyl-phenyl)-thiazol-4-yl]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / H₂S; pyridine; Et₃N / 10 h / 20 °C

2: 68 percent / tetrahydrofuran / 12 h

With pyridine; hydrogen sulfide; triethylamine; In tetrahydrofuran;