2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-

Base Information

Chemical Name:2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-
CAS No.:653604-45-6
Molecular Formula:C24H22N2O
Molecular Weight:354.451
Hs Code.:
DSSTox Substance ID:DTXSID60459636
Wikidata:Q82283457

Synonyms:653604-45-6;2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-;DTXSID60459636

Suppliers and Price of 2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-

Chemical Property:

XLogP3:6.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:354.173213330
Heavy Atom Count:27
Complexity:558

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(C1)CC2=CC(=CC=C2)NC(=O)C3=CC4=C(C=C3)C=C(C=C4)C#N

Technology Process of 2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]-

There total 9 articles about 2-Naphthalenecarboxamide, 6-cyano-N-[3-(cyclopentylmethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7333-52-0
cyclopenthyltriphenylphosphonium bromide

: 653604-45-6
6-[N-(3-(cyclopentylmethyl)phenyl)carbamyl]-2-naphthalenecarbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: BuLi / tetrahydrofuran / -78 - 0 °C

1.2: tetrahydrofuran / -78 - 20 °C

2.1: 992 mg / H₂; AcOH / Pd/C / methanol / 18 h / 20 °C / 760 Torr

3.1: Et₃N; DMAP / CH₂Cl₂ / 18 h / 20 °C

With dmap; n-butyllithium; hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm0300072

Reference yield:

: 1-cyclopentylidenemethyl-3-nitro-benzene

: 653604-45-6
6-[N-(3-(cyclopentylmethyl)phenyl)carbamyl]-2-naphthalenecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 992 mg / H₂; AcOH / Pd/C / methanol / 18 h / 20 °C / 760 Torr

2: Et₃N; DMAP / CH₂Cl₂ / 18 h / 20 °C

With dmap; hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1021/jm0300072