2-(Morpholin-4-yl)cyclohexan-1-amine

Base Information

Chemical Name:2-(Morpholin-4-yl)cyclohexan-1-amine
CAS No.:65430-31-1
Molecular Formula:C10H20N2O
Molecular Weight:184.282
Hs Code.:
European Community (EC) Number:878-489-2

Synonyms:2-(morpholin-4-yl)cyclohexan-1-amine;65430-31-1;2-morpholin-4-ylcyclohexanamine;2-morpholin-4-ylcyclohexan-1-amine;(1R,2R)-2-(4-Morpholinyl)cyclohexanamine;(1S,2S)-2-(4-Morpholinyl)cyclohexanamine;SCHEMBL798263;AKOS009150035;EN300-108654;F8880-7913;Z285186686

Suppliers and Price of 2-(Morpholin-4-yl)cyclohexan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(Morpholin-4-yl)cyclohexan-1-amine

Chemical Property:

XLogP3:0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:184.157563266
Heavy Atom Count:13
Complexity:157

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C(C1)N)N2CCOCC2

Technology Process of 2-(Morpholin-4-yl)cyclohexan-1-amine

There total 5 articles about 2-(Morpholin-4-yl)cyclohexan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14909-79-6
trans-2-morpholinocyclohexanol

: 65430-31-1,291776-02-8
(+/-)-trans-2-(morpholin-4-yl)cyclohexanamine

Guidance literature:: With chlorosulfonic acid; Erhitzen des Reaktionsprodukts mit wss. NH₃;

Reference yield:

: 286-20-4
cyclohexane-1,2-epoxide

: 65430-31-1,291776-02-8
(+/-)-trans-2-(morpholin-4-yl)cyclohexanamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 18 h / Heating

2.1: MsCl; Et₃N / diethyl ether / 0 - 20 °C

2.2: aq. NH₃ / diethyl ether / 16 h / 20 °C

With methanesulfonyl chloride; triethylamine; In diethyl ether; ethanol;
DOI:10.1002/chem.200400607