Poly(8-bromodeoxyadenylic acid)

Base Information

• Chemical Name: Poly(8-bromodeoxyadenylic acid)
• CAS No.: 90968-89-1
• Molecular Formula: C10H12BrN5O3
• Molecular Weight: 330.141

Synonyms:poly(8-bromodeoxyadenylic acid)

Chemical Property of Poly(8-bromodeoxyadenylic acid)

Chemical Property:

Purity/Quality:

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Technology Process of Poly(8-bromodeoxyadenylic acid)

There total 6 articles about Poly(8-bromodeoxyadenylic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2'-deoxy-D-adenosine (958-09-8,7005-15-4) → 8-bromo-2'-deoxyadenosine (14985-44-5,90968-89-1)

Guidance literature:

With bromine; sodium acetate; acetic acid; In water; at 20 - 50 ℃;

DOI:10.1016/j.bmc.2017.03.045

Reference yield:

2'-Deoxyadenosine monohydrate → 8-bromo-2'-deoxyadenosine (14985-44-5,90968-89-1)

Guidance literature:

With sodium hydroxide; bromine; sodium thiosulfate;

Reference yield:

→ 2'-deoxy-7,8-dihydro-6-N-acetyladenosin-8-one + 8-bromo-2'-deoxyadenosine (14985-44-5,90968-89-1)

Guidance literature:

upstream raw materials:

2'-deoxy-D-adenosine

Downstream raw materials:

8-(methylthio)-2'-deoxyadenosine

5-(6-amino-8-(4-(trifluoromethyl)styryl)-9H-purin-9-yl)-2-((bis(4-methoxy-phenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-ol

8-<10-(benzyloxycarbonyl)aminodecyl>-amino-2'-deoxyadenosine

8-bromo-N⁶-phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

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