Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]-

Base Information

• Chemical Name: Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]-
• CAS No.: 65577-30-2
• Molecular Formula: C15H18NO2P
• Molecular Weight: 275.287
• European Community (EC) Number: 692-012-3
• DSSTox Substance ID: DTXSID00422889
• Mol file: 65577-30-2.mol

Synonyms:Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]-;65577-30-2;Oprea1_429827;SCHEMBL1764563;DTXSID00422889;STK821161;AKOS003614692;AKOS016335805;{1-[(diphenylmethyl)amino]ethyl}phosphinic acid

Chemical Property of Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 274.09969078
• Heavy Atom Count: 19
• Complexity: 268

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(NC(C1=CC=CC=C1)C2=CC=CC=C2)[P+](=O)O

Technology Process of Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]-

There total 3 articles about Phosphinic acid, [1-[(diphenylmethyl)amino]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

aminodiphenylmethane hydrochloride (5267-34-5) + acetaldehyde (75-07-0,9002-91-9) → 1-(benzhydrylamino)ethylphosphinic acid (65577-30-2)

Guidance literature:

With hypophosphorous acid; In water; for 2h; Heating;

Reference yield:

Benzhydryl-eth-(E)-ylidene-amine (80993-20-0) → 1-(benzhydrylamino)ethylphosphinic acid (65577-30-2)

Guidance literature:

Multi-step reaction with 2 steps

1: benzene / Ambient temperature

2: 85percent aq. EtOH / Ambient temperature

With ethanol; In benzene;

DOI:10.1055/s-1987-28133

Reference yield:

C21H34NO2PSi2 → 1-(benzhydrylamino)ethylphosphinic acid (65577-30-2)

Guidance literature:

With ethanol; Yield given; Ambient temperature;

DOI:10.1055/s-1987-28133

upstream raw materials:

aminodiphenylmethane hydrochloride

acetaldehyde

Benzhydryl-eth-(E)-ylidene-amine

Downstream raw materials:

(1-aminoethyl)phosphinic acid