7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole

Base Information

Chemical Name:7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole
CAS No.:6560-32-3
Molecular Formula:C15H18N2O3
Molecular Weight:274.32
Hs Code.:
DSSTox Substance ID:DTXSID60521266
Wikidata:Q82385650

Synonyms:6560-32-3;DTXSID60521266;7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole

Suppliers and Price of 7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:274.13174244
Heavy Atom Count:20
Complexity:335

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCN1CCC2=CNC3=CC4=C(C=C32)OCO4

Technology Process of 7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole

There total 4 articles about 7-[2-(Morpholin-4-yl)ethyl]-2H,5H-[1,3]dioxolo[4,5-f]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 6724-72-7
1-(5H-[1,3]dioxolo[4,5-f]indol-7-yl)-2-morpholinoethane-1,2-dione

: 6560-32-3
7-(2-Morpholin-4-yl-ethyl)-5H-[1,3]dioxolo[4,5-f]indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;
DOI:10.1002/jhet.5570200438

Reference yield:

: 15794-43-1
6,β-dinitro-3,4-methylenedioxystyrene

: 6560-32-3
7-(2-Morpholin-4-yl-ethyl)-5H-[1,3]dioxolo[4,5-f]indole

Guidance literature:: Multi-step reaction with 4 steps

1: 64 percent / H₂ / 10percent Pd/C / ethanol; acetic acid; ethyl acetate / 0.75 h / 2068.6 - 2844.3 Torr

2: diethyl ether / 0.5 h / 0 °C

3: 58 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9

4: 68 percent / LiAlH₄ / tetrahydrofuran / Heating

With lithium aluminium tetrahydride; hydrogen; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethanol; acetic acid; ethyl acetate;
DOI:10.1002/jhet.5570200438

Reference yield:

: 267-48-1
5,6-methylenedioxyindole

: 6560-32-3
7-(2-Morpholin-4-yl-ethyl)-5H-[1,3]dioxolo[4,5-f]indole

Guidance literature:: Multi-step reaction with 3 steps

1: diethyl ether / 0.5 h / 0 °C

2: 58 percent / tetrahydrofuran; diethyl ether / 0 °C / pH > 9

3: 68 percent / LiAlH₄ / tetrahydrofuran / Heating

With lithium aluminium tetrahydride; In tetrahydrofuran; diethyl ether;
DOI:10.1002/jhet.5570200438