4-benzyl-N-phenylpiperazine-1-carboxamide

Base Information

Chemical Name:4-benzyl-N-phenylpiperazine-1-carboxamide
CAS No.:65766-74-7
Molecular Formula:C18H21N3O
Molecular Weight:295.384
Hs Code.:
DSSTox Substance ID:DTXSID90352681
Nikkaji Number:J740.552I
Wikidata:Q82129947
ChEMBL ID:CHEMBL1619418

Synonyms:4-benzyl-N-phenylpiperazine-1-carboxamide;65766-74-7;CHEMBL1619418;4-Benzyl-piperazine-1-carboxylic acid phenylamide;4-benzyl-N-phenyl-1-piperazinecarboxamide;Cambridge id 5730361;Oprea1_589291;Oprea1_802506;SCHEMBL3596348;DTXSID90352681;KPXKZXWDRQMAJJ-UHFFFAOYSA-N;BDBM50394643;CCG-55074;AKOS000665774;AB00095053-01;AQ-360/40219376;SR-01000644122-1;Z44585957

Suppliers and Price of 4-benzyl-N-phenylpiperazine-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-benzyl-N-phenylpiperazine-1-carboxamide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:295.168462302
Heavy Atom Count:22
Complexity:340

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C(=O)NC3=CC=CC=C3

Technology Process of 4-benzyl-N-phenylpiperazine-1-carboxamide

There total 5 articles about 4-benzyl-N-phenylpiperazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 474711-91-6
N-phenylpiperazine-1-carboxamide hydrochloride

: 100-52-7
benzaldehyde

: 65766-74-7
4-benzyl-piperazine-1-carboxylic acid anilide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; tetramethylammonium triacetoxyborohydride; In tetrahydrofuran; at 20 ℃; Inert atmosphere;
DOI:10.1021/ml300186g

Reference yield:

: 2759-28-6
1-phenylmethylpiperazine

: 103-71-9
phenyl isocyanate

: 65766-74-7
4-benzyl-piperazine-1-carboxylic acid anilide

Guidance literature:: In ethanol;

Reference yield:

: 295341-38-7
tert-butyl 4-(phenylcarbamoyl)piperazine-1-carboxylate

: 65766-74-7
4-benzyl-piperazine-1-carboxylic acid anilide

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 1,4-dioxane; dichloromethane / 20 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine; tetramethylammonium triacetoxyborohydride / tetrahydrofuran / 20 °C / Inert atmosphere

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; tetramethylammonium triacetoxyborohydride; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1021/ml300186g