1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-

Base Information

Chemical Name:1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-
CAS No.:6578-89-8
Molecular Formula:C₁₆H₁₃N₃OS
Molecular Weight:295.365
Hs Code.:
DSSTox Substance ID:DTXSID80394292
Nikkaji Number:J1.897.784B

Synonyms:6578-89-8;1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-;DTXSID80394292;N-(4-Methoxybenzylidene)-5-phenyl-1,3,4-thiadiazole-2-amine

Suppliers and Price of 1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:295.07793322
Heavy Atom Count:21
Complexity:338

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=NC2=NN=C(S2)C3=CC=CC=C3

Technology Process of 1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl-

There total 3 articles about 1,3,4-Thiadiazol-2-amine, N-[(4-methoxyphenyl)methylene]-5-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₈H₉N₃S

: 6578-89-8
(4-methoxy-benzylidene)-(5-phenyl-[1,3,4]thiadiazol-2-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: iron(III) chloride / water / 0.75 h / 80 - 90 °C

2: acetic acid / ethanol / 6 h / Reflux

With iron(III) chloride; acetic acid; In ethanol; water;
DOI:10.14233/ajchem.2022.23591

Reference yield:

: 100-52-7
benzaldehyde

: 6578-89-8
(4-methoxy-benzylidene)-(5-phenyl-[1,3,4]thiadiazol-2-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol; water

2: iron(III) chloride / water / 0.75 h / 80 - 90 °C

3: acetic acid / ethanol / 6 h / Reflux

With iron(III) chloride; acetic acid; In ethanol; water;
DOI:10.14233/ajchem.2022.23591

Reference yield:

: 65-85-0,8013-63-6
benzoic acid

: 6578-89-8
(4-methoxy-benzylidene)-(5-phenyl-[1,3,4]thiadiazol-2-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 2 h / Reflux

2: 0.05 h / Microwave irradiation

With sulfuric acid;