2-Methyl-6-(trifluoromethyl)quinoline

Base Information

Chemical Name:2-Methyl-6-(trifluoromethyl)quinoline
CAS No.:66023-21-0
Molecular Formula:C11H8F3N
Molecular Weight:211.186
Hs Code.:
UNII:KXL624TP51
Nikkaji Number:J1.495.485F

Synonyms:2-methyl-6-(trifluoromethyl)quinoline;66023-21-0;2-methyl-6-trifluoromethylquinoline;Torcetrapib metabolite M3;6-(Trifluoromethyl)quinaldine;Quinoline, 2-methyl-6-(trifluoromethyl)-;KXL624TP51;6-trifluoromethylquinaldine;UNII-KXL624TP51;SCHEMBL5090080;HMS1659H01;6-trifluoromethyl-2-methylquinoline;2-methyl-6-trifluoromethyl quinoline;MFCD07807945;AKOS022491930;CS-15793;SY343270;CS-0045218;D72715

Suppliers and Price of 2-Methyl-6-(trifluoromethyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-Methyl-6-(trifluoromethyl)quinoline

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:211.06088375
Heavy Atom Count:15
Complexity:226

Purity/Quality:: NLT 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC2=C(C=C1)C=C(C=C2)C(F)(F)F

Technology Process of 2-Methyl-6-(trifluoromethyl)quinoline

There total 2 articles about 2-Methyl-6-(trifluoromethyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 877-42-9
6-Bromo-2-methyl-quinoline

: 1895006-01-5
dimesityl(trifluoromethyl)sulfonium trifluoromethanesulfonate

: 66023-21-0
2-methyl-6-(trifluoromethyl)-quinoline

Guidance literature:: With dilithium tetrabromocuprate; 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)-2-trisilanol; [Ir(2-(2,4-difluorophenyl)-5-(methyl)pyridinyl)₂(4,4′-bis(tert-butyl)bipyridine)]*PF₆; sodium carbonate; In acetone; at 35 ℃; Irradiation;
DOI:10.1126/science.aat4133

Reference yield: 49.0%

: 4784-77-4,39616-19-8,29576-14-5
(E)-1-Bromo-2-butene

: 258351-71-2
1-(p-tolyl)-2-(p-(trifluoromethyl)phenyl)diazene

: 66023-21-0
2-methyl-6-(trifluoromethyl)-quinoline

: 877-43-0
2,6-dimethylquinoline

Guidance literature:: With copper(l) iodide; In 1,2-dichloro-ethane; at 120 ℃; for 12h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.5b03009