1895006-01-5 Usage
Uses
Under a dual catalytic copper/photoredox manifold, the Mes-Umemoto reagent has been demonstrated by the MacMillan lab to be an excellent reagent for the trifluoromethylation of alkyl halides and aryl halides to yield alkyl-CF3 and aryl-CF3 in high yields. In both cases, these reactions exhibit wide substrate scope with good functional group tolerance. More specifically, a variety of 5-membered and 6-membered heteroaryl halides can be readily converted to the corresponding trifluoromethylheteroarenes under mild conditions. To be use in conjunction with supersilanol (902489) and Ir photocatalyst (902217 or 902225).
Check Digit Verification of cas no
The CAS Registry Mumber 1895006-01-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,8,9,5,0,0 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1895006-01:
(9*1)+(8*8)+(7*9)+(6*5)+(5*0)+(4*0)+(3*6)+(2*0)+(1*1)=185
185 % 10 = 5
So 1895006-01-5 is a valid CAS Registry Number.
1895006-01-5Relevant articles and documents
Palladium-Catalyzed Arylation of Arylboronic Acids with Yagupolskii-Umemoto Reagents
Wang, Shi-Meng,Wang, Xiao-Yan,Qin, Hua-Li,Zhang, Cheng-Pan
, p. 6542 - 6546 (2016)
A Pd-catalyzed Suzuki cross-coupling of arylboronic acids with Yagupolskii-Umemoto reagents was explored. In contrary to trifluoromethylations, the Pd-catalyzed reaction of R-B(OH)2 and [Ar2SCF3]+[OTf]- provided the arylation products (R-Ar) in good to high yields. The reaction confirms that the S-Ar bonds of [Ar2SCF3]+[OTf]- can be readily cleaved in the presence of Pd complexes. The relatively electron-poor aryl groups of asymmetric [Ar1Ar2SCF3]+[OTf]- salts are more favorably transferred compared to the electron-rich ones. This reaction represents the first report of utilization of [Ar2SCF3]+[OTf]- as arylation reagents in organic synthesis.
