1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate)

Base Information

Chemical Name:1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate)
CAS No.:660843-23-2
Molecular Formula:C10H16N2O4.C2HF3O2
Molecular Weight:342.272
Hs Code.:

Synonyms:

Suppliers and Price of 1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 21 raw suppliers

Chemical Property of 1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate)

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Use Description 1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate) is a chemical compound with diverse applications in different fields. In the field of organic chemistry and chemical research, it serves as a versatile intermediate and reagent for the synthesis of various organic compounds and pharmaceuticals, contributing to the development of new materials and drug candidates. Its role is pivotal in advancing organic synthesis and drug discovery efforts. Additionally, in the realm of biotechnology and molecular biology, it can be utilized in the modification of biomolecules and as a linker for the conjugation of biomolecules to surfaces or other molecules, enabling the development of diagnostics and biotechnological tools. Furthermore, in the pharmaceutical industry, it may find applications as a chemical intermediate in the synthesis of specific drug molecules, potentially contributing to drug development and manufacturing. Its multifaceted utility underscores its significance in organic synthesis, biotechnology, and pharmaceutical research, where it plays various roles in advancing chemical and biomedical science.

Technology Process of 1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate)

There total 7 articles about 1H-Pyrrole-2,5-dione, 1-[2-[2-(2-aminoethoxy)ethoxy]ethyl]-, mono(trifluoroacetate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 660843-21-0
tert-butyl N-(2-{2-[2-(2,5-dioxo-2,5-dihydro-iH-pyrrol-1-yl)ethoxy]ethoxy}ethyl)carbamate

: 76-05-1
trifluoroacetic acid

: 660843-23-2
1-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione trifluoroacetate

Guidance literature:: In chloroform; at 20 ℃; for 2h;
DOI:10.1039/b907579h

Reference yield:

: 950683-55-3
{2-[2-(2-azidoethoxy)ethoxy]ethyl}carbamic acid tert-butyl ester

: 660843-23-2
1-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: triphenylphosphine / tetrahydrofuran / 5 h

1.2: 2 h

2.1: sodium hydrogencarbonate / water / 1.25 h / 0 - 20 °C / Saturated solution

3.1: dichloromethane / 0.17 h

With sodium hydrogencarbonate; triphenylphosphine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/cbic.201000280

Reference yield:

: 1245727-44-9
2-(2-(2-azidoethoxy)ethoxy)ethanamine hydrochloride

: 660843-23-2
1-{2-[2-(2-aminoethoxy)ethoxy]ethyl}-2,5-dihydro-1H-pyrrole-2,5-dione trifluoroacetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: triethylamine / dichloromethane / 0.83 h

2.1: triphenylphosphine / tetrahydrofuran / 5 h

2.2: 2 h

3.1: sodium hydrogencarbonate / water / 1.25 h / 0 - 20 °C / Saturated solution

4.1: dichloromethane / 0.17 h

With sodium hydrogencarbonate; triethylamine; triphenylphosphine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1002/cbic.201000280