1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-

Base Information

Chemical Name:1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-
CAS No.:80429-21-6
Molecular Formula:C₂₄H₂₅ClN₄
Molecular Weight:404.942
Hs Code.:
DSSTox Substance ID:DTXSID70230312
Wikidata:Q83110797

Synonyms:1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-;2-(2-(4-(4-Chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-1H-naphth(1,2-d)imidazole;80429-21-6;C24H25ClN4;SCHEMBL10601879;C24-H25-Cl-N4;DTXSID70230312;ZNFPJYOJFBZARP-UHFFFAOYSA-N;LS-95233;2-[2-[4-(4-chlorophenyl)piperazinyl]ethyl]-1-methyl-1H-naphth[1,2-d]imidazole

Suppliers and Price of 1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-

Chemical Property:

Vapor Pressure:7.84E-16mmHg at 25°C
Boiling Point:631°C at 760 mmHg
Flash Point:335.4°C
Density:1.25g/cm³
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:404.1767745
Heavy Atom Count:29
Complexity:529

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=NC2=C1C3=CC=CC=C3C=C2)CCN4CCN(CC4)C5=CC=C(C=C5)Cl

Technology Process of 1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl-

There total 7 articles about 1H-Naphth(1,2-d)imidazole, 2-(2-(4-(4-chlorophenyl)-1-piperazinyl)ethyl)-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 80429-21-6
2-[2-[4-(4-chlorophenyl)-1-piperazinyl]ethyl]-1-methyl-1H-naphth[1,2-d]imidazole

Guidance literature:

Reference yield: 72.0%

: 38212-33-8
4-(4-chlorophenyl) piperazine

: 80428-96-2
2-(2-chloroethyl)-1-methyl-1H-naphth<1,2-d>imidazole

: 80429-21-6
2-[2-[4-(4-chlorophenyl)-1-piperazinyl]ethyl]-1-methyl-1H-naphth[1,2-d]imidazole

Guidance literature:: In pentan-1-ol; for 2h; Heating;
DOI:10.1016/0223-5234(87)90053-5

Reference yield:

: 5467-58-3
1-bromo-4-methoxynaphthalene

: 80429-21-6
2-[2-[4-(4-chlorophenyl)-1-piperazinyl]ethyl]-1-methyl-1H-naphth[1,2-d]imidazole

Guidance literature:: Multi-step reaction with 5 steps

1: 49 percent / 99percent nitric acid, 96percent sulfuric acid / acetic anhydride / 0.17 h / -30 °C

2: 92 percent / dimethylformamide / 1 h / Ambient temperature

3: 91 percent / triethylamine, H₂ / 10percent palladium on carbon / methanol / 1.5 h / 3800 Torr / Ambient temperature

4: 1.) triethylamine; 2.) 5percent HCl / 1.) CH₂Cl₂, refl., 30 min; 2.) 60 deg C, 3 h

5: 72 percent / pentan-1-ol / 2 h / Heating

With hydrogenchloride; sulfuric acid; hydrogen; nitric acid; triethylamine; palladium on activated charcoal; In methanol; pentan-1-ol; acetic anhydride; N,N-dimethyl-formamide;
DOI:10.1016/0223-5234(87)90053-5