5467-58-3

Basic information

• Product Name: 1-bromo-4-methoxy-naphthalene
• Synonyms: 1-bromo-4-methoxy-naphthalene;1-Methoxy-4-broMonaphthalene;4-BroMo-1-Methoxynaphthalene;4-Methoxy-1-broMonaphthalene;NSC 25655
• CAS NO: 5467-58-3
• Molecular Formula: C₁₁H₉BrO
• Molecular Weight: 237.09
• Product Categories: Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 5467-58-3.mol
• Article Data: 3

Chemical Properties

• Melting Point: 195-196 °C
• Boiling Point: 325.4 °C at 760 mmHg
• Flash Point: 135 °C
• Appearance: /
• Density: 1.447 g/cm³
• Vapor Pressure: 0.000438mmHg at 25°C
• Refractive Index: 1.632
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-bromo-4-methoxy-naphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-4-methoxy-naphthalene(5467-58-3)
• EPA Substance Registry System: 1-bromo-4-methoxy-naphthalene(5467-58-3)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 5467-58-3(Hazardous Substances Data)

Usage

Chemical Properties

Oil

Synthesis Reference(s)

The Journal of Organic Chemistry, 11, p. 399, 1946 DOI: 10.1021/jo01174a017

InChI:InChI=1/C11H9BrO/c1-13-11-7-6-10(12)8-4-2-3-5-9(8)11/h2-7H,1H3

Upstream product

• 100-66-3 methoxybenzene 
• 2216-69-5 1-Methoxynaphthalene 

Downstream Products

• 269410-16-4 2-(4-methoxy-naphthalen-1-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 
• 2216-69-5 1-Methoxynaphthalene 
• 219834-95-4 (4-methoxynaphthalen-1-yl)boronic acid 
• 72774-00-6 1-methoxy-4-phenylnaphthalene 
• 16820-54-5 1-hydroxymethyl-4-methoxy-naphthalene 
• 36831-92-2 2-(4-bromo-1-hydroxy-[2]naphthoyl)-benzoic acid 
• 571-57-3 4-bromo-1-naphthol 
• 163397-20-4 (1-methoxynaphthalen-4-yl)(phenyl)sulfane 
• 38063-26-2 5-hydroxybenzophenanthrene 

Relevant articles and documents

Aerobic oxidative bromination of arenes using an ionic liquid as both the catalyst and the solvent

A method for the bromination of alkoxy-substituted benzenes and naphthalenes was developed by using the residual oxygen in the reaction tube as the oxidant, and [Bmim]NO3 (1-butyl-3-methylimidazolium nitrate) ionic liquid as both the catalyst and the solvent. No other reagent apart from the ionic liquid and molecular bromine was used in the reactions, and basically all the bromine atoms in the bromine source were transferred to the bromination products, showing that the presented protocol is highly atom economic and practical.

An efficient and regioselective oxybromination of aromatic compounds using potassium bromide and oxone

A simple, efficient and regioselective method for oxybromination of aromatics is reported. The electrophilic substitution of bromine generated in situ from potassium bromide using oxone as an oxidant for the first time.