Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate

Base Information

Chemical Name:Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate
CAS No.:661487-18-9
Molecular Formula:C17H21N3O2
Molecular Weight:299.373
Hs Code.:2933990090
DSSTox Substance ID:DTXSID70434651
Wikidata:Q82249117
ChEMBL ID:CHEMBL2435653
Mol file:661487-18-9.mol

Synonyms:661487-18-9;TERT-BUTYL 3-PHENYL-6,7-DIHYDRO-1H-PYRAZOLO[4,3-C]PYRIDINE-5(4H)-CARBOXYLATE;tert-butyl 3-phenyl-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridine-5-carboxylate;CHEMBL2435653;tert-Butyl 3-phenyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate;Tert-Butyl3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate;SCHEMBL10095067;DTXSID70434651;BDBM50441668;AKOS015968935;CS-0054958;A901815

Suppliers and Price of Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 95+%
1g
$ 793.00

Chemenu
tert-butyl3-phenyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate 95+%
250mg
$ 1266.00

Chemenu
tert-butyl3-phenyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate 95+%
100mg
$ 974.00

American Custom Chemicals Corporation
TERT-BUTYL-3-PHENYL-6,7-DIHYDRO-1H-PYRAZOLO-[4,3-C]-PYRIDINE-5-(4H)-CARBOXYLATE 95.00%
5MG
$ 498.82

Alichem
tert-Butyl3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate
1g
$ 868.29

Total 10 raw suppliers

Chemical Property of Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:508.52oC at 760 mmHg
Flash Point:261.344oC
PSA：58.22000
Density:1.191g/cm3
LogP:3.30780
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:299.16337692
Heavy Atom Count:22
Complexity:401

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC2=C(C1)C(=NN2)C3=CC=CC=C3

Technology Process of Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate

There total 5 articles about Tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-C]pyridine-5(4H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: tert-butyl 3-benzoyl-4-oxopiperidine-1-carboxylate

: 661487-18-9
tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

Guidance literature:: With hydrazine hydrate; In ethanol; at 0 - 20 ℃; for 4h;
DOI:10.1039/C6NJ02671K

Reference yield: 90.0%

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 98-88-4
benzoyl chloride

: 661487-18-9
tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

Guidance literature:: N-tert-butyloxycarbonylpiperidin-4-one; With morpholine; toluene-4-sulfonic acid; In toluene; for 16h; Dean-Stark; Reflux; Inert atmosphere;

benzoyl chloride; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 4h;

With hydrazine; In ethanol; at 20 ℃; for 16h;
DOI:10.1016/j.ejmech.2013.08.036

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 661487-18-9
tert-butyl 3-phenyl-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: morpholine; toluene-4-sulfonic acid / toluene / 16 h / 100 °C / Dean-Stark; Inert atmosphere

1.2: 4 h / 0 - 20 °C / Inert atmosphere; Dean-Stark

2.1: hydrazine hydrate / ethanol / 4 h / 0 - 20 °C

With morpholine; toluene-4-sulfonic acid; hydrazine hydrate; In ethanol; toluene; 1.1: |Stork Enamine Alkylation / 1.2: |Stork Enamine Alkylation;
DOI:10.1039/C6NJ02671K