4'-Fluoro-2-methoxy-1,1'-biphenyl

Base Information

Chemical Name:4'-Fluoro-2-methoxy-1,1'-biphenyl
CAS No.:66175-47-1
Molecular Formula:C13H11FO
Molecular Weight:202.228
Hs Code.:
DSSTox Substance ID:DTXSID30517853
Nikkaji Number:J3.536.860D
Wikidata:Q82380085

Synonyms:4'-Fluoro-2-methoxy-1,1'-biphenyl;66175-47-1;SCHEMBL5690752;DTXSID30517853;VKAHDWFYEKYLIN-UHFFFAOYSA-N;4'-fluoro[1,1'-biphenyl]-2-yl methyl ether

Suppliers and Price of 4'-Fluoro-2-methoxy-1,1'-biphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4'-Fluoro-2-methoxy-1,1'-biphenyl

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:202.079393132
Heavy Atom Count:15
Complexity:187

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=CC=C(C=C2)F

Technology Process of 4'-Fluoro-2-methoxy-1,1'-biphenyl

There total 1 articles about 4'-Fluoro-2-methoxy-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 578-57-4
2-bromoanisole

: 352-33-0
1-Chloro-4-fluorobenzene

: 398-23-2
4,4'-difluorobiphenyl

: 4877-93-4
2,2'-Dimethoxybiphenyl

: 66175-47-1
4'-fluoro-2-methoxyl-1,1'-biphenyl

Guidance literature:: With NaH-t-AmONa-Ni(OAc)2-bpy-KI; In tetrahydrofuran; benzene; at 63 ℃; for 2h; Yields of byproduct given;
DOI:10.1021/jo00281a028

Reference yield: 70.0%

: 66175-47-1
4'-fluoro-2-methoxyl-1,1'-biphenyl

: 73183-34-3
bis(pinacol)diborane

: 881314-65-4
2-(2'-methoxy-[1,1'-biphenyl]-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; iron(II) chloride; lithium hexamethyldisilazane; In toluene; at 110 ℃; for 12h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.orglett.8b02228