2-Amino-4,5-dichloro-3-nitropyridine

Base Information

• Chemical Name: 2-Amino-4,5-dichloro-3-nitropyridine
• CAS No.: 662116-67-8
• Molecular Formula: C5H3Cl2N3O2
• Molecular Weight: 208.004
• Hs Code.: 2933399090
• Mol file: 662116-67-8.mol

Synonyms:2-amino-3-nitro-4,5-dichloropyridine;RW3676;4,5-dichloro-3-nitropyridin-2-ylamine;2-Amino-4,5-dichloro-3-nitropyridine;

Chemical Property of 2-Amino-4,5-dichloro-3-nitropyridine

Chemical Property:

• Boiling Point: 337.2±37.0 °C(Predicted)
• PKA: -0.86±0.50(Predicted)
• PSA: 85.46000
• Density: 1.723±0.06 g/cm3(Predicted)
• LogP: 2.33210
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

4,5-Dichloro-3-nitropyridin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Amino-4,5-dichloro-3-nitropyridine

There total 6 articles about 2-Amino-4,5-dichloro-3-nitropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-chloro-3-nitro-2-pyridinamine (6980-08-1) → 4,5-dichloro-3-nitropyridin-2-ylamine (662116-67-8)

Guidance literature:

With N-chloro-succinimide; In acetonitrile; at 80 ℃; for 1h;

Reference yield: 70.0%

4,5-dichloro-2-aminopyridine (188577-68-6) → 4,5-dichloro-3-nitropyridin-2-ylamine (662116-67-8)

Guidance literature:

With sulfuric acid; nitric acid; at 30 ℃; for 3h;

Reference yield: 59.0%

N-(4,5-dichloropyridin-2-yl)nitramide → 4,5-dichloro-3-nitropyridin-2-ylamine (662116-67-8)

Guidance literature:

With sulfuric acid; at 40 ℃; for 2.5h;

upstream raw materials:

N-(4,5-dichloropyridin-2-yl)-2,2-dimethylpropanamide

4,5-dichloro-2-aminopyridine

2-Amino-4-chloropyridine

4-chloro-3-nitro-2-pyridinamine

Downstream raw materials:

2,3-diamino-4,5-dichloropyridine

5-chloro-4-(4-(4-chlorobenzyl)piperazin-1-yl)-3-nitropyridin-2-amine

5-chloro-4-(4-(2-chloro-6-fluorobenzyl)piperazin-1-yl)-3-nitropyridin-2-amine

5-chloro-3-nitro-4-(4-phenethylpiperazin-1-yl)pyridin-2-amine