2-imidazoledistamycin

Base Information

Chemical Name:2-imidazoledistamycin
CAS No.:142211-78-7
Molecular Formula:C₂₁H₂₆N₁₀O₄*ClH
Molecular Weight:518.963
Hs Code.:
Mol file:142211-78-7.mol

Synonyms:1H-Imidazole-2-carboxamide,N-[5-[[(3-amino-3-iminopropyl)amino]carbonyl]-1-methyl-1H-pyrrol-3-yl]-4-[[[4-(formylamino)-1-methyl-1H-pyrrol-2-yl]carbonyl]amino]-1-methyl-,monohydrochloride (9CI)

Suppliers and Price of 2-imidazoledistamycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-imidazoledistamycin

Chemical Property:

PSA：197.44000
LogP:3.01430

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-imidazoledistamycin

There total 10 articles about 2-imidazoledistamycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 128293-62-9
ethyl 4-amino-1-methylimidazole-2-carboxylate

: 142211-78-7
3-<1-methyl-4-<1-methyl-4-<1-methyl-4-(formylamino)pyrrole-2-carboxamido>imidazole-2-carboxamido>pyrrole-2-carboxamido>propionamidine hydrochloride

Guidance literature:: Multi-step reaction with 7 steps

1: Et₃N / CH₂Cl₂ / 6 h / Ambient temperature

2: 89 percent / 1 M LiOH / ethanol / 2 h

3: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride (EDCI) / dimethylformamide / 12 h / Ambient temperature

4: HCl(g) / 2 h / 0 - 20 °C

5: ammonia / ethanol / 8 h / Ambient temperature

6: H₂ / 10percent Pd/C / methanol / 4 h / 2280 Torr / Ambient temperature

7: formic acid / 12 h / Ambient temperature

With hydrogenchloride; lithium hydroxide; ammonia; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In methanol; formic acid; ethanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 109012-23-9
ethyl 1-methyl-4-nitroimidazole-2-carboxylate

: 142211-78-7
3-<1-methyl-4-<1-methyl-4-<1-methyl-4-(formylamino)pyrrole-2-carboxamido>imidazole-2-carboxamido>pyrrole-2-carboxamido>propionamidine hydrochloride

Guidance literature:: Multi-step reaction with 8 steps

1: H₂ / 10percent Pd/C / ethyl acetate; methanol / Ambient temperature

2: Et₃N / CH₂Cl₂ / 6 h / Ambient temperature

3: 89 percent / 1 M LiOH / ethanol / 2 h

4: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride (EDCI) / dimethylformamide / 12 h / Ambient temperature

5: HCl(g) / 2 h / 0 - 20 °C

6: ammonia / ethanol / 8 h / Ambient temperature

7: H₂ / 10percent Pd/C / methanol / 4 h / 2280 Torr / Ambient temperature

8: formic acid / 12 h / Ambient temperature

With hydrogenchloride; lithium hydroxide; ammonia; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; palladium on activated charcoal; In methanol; formic acid; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 97950-77-1
3-(1-methyl-4-aminopyrrole-2-carboxamido)propionitrile

: 142211-78-7
3-<1-methyl-4-<1-methyl-4-<1-methyl-4-(formylamino)pyrrole-2-carboxamido>imidazole-2-carboxamido>pyrrole-2-carboxamido>propionamidine hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1: 1-ethyl-3-<3-(dimethylamino)propyl>carbodiimide hydrochloride (EDCI) / dimethylformamide / 12 h / Ambient temperature

2: HCl(g) / 2 h / 0 - 20 °C

3: ammonia / ethanol / 8 h / Ambient temperature

4: H₂ / 10percent Pd/C / methanol / 4 h / 2280 Torr / Ambient temperature

5: formic acid / 12 h / Ambient temperature

With hydrogenchloride; ammonia; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium on activated charcoal; In methanol; formic acid; ethanol; N,N-dimethyl-formamide;