7-Bromo-3-hydroxyisoquinoline

Base Information

• Chemical Name: 7-Bromo-3-hydroxyisoquinoline
• CAS No.: 662139-46-0
• Molecular Formula: C9H6BrNO
• Molecular Weight: 224.05400
• Hs Code.: 2933499090
• Mol file: 662139-46-0.mol

Synonyms:7-bromo-3-hydroxy-isoquinoline;7-bromanyl-2H-isoquinolin-3-one;7-Bromoisoquinolin-3(2H)-one;7-Bromoisoquinolin-3-ol;

Chemical Property of 7-Bromo-3-hydroxyisoquinoline

Chemical Property:

• PSA: 32.86000
• LogP: 2.29060
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99%, ^*data from raw suppliers

7-Bromo-3-hydroxyisoquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-Bromo-3-hydroxyisoquinoline

There total 1 articles about 7-Bromo-3-hydroxyisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(3-bromobenzyl)-2,2-dimethoxyacetamide (1175271-87-0) → 7-bromoisoquinolin-3-ol (662139-46-0) + 5-bromoisoquinolin-3-ol (1175271-86-9)

Guidance literature:

N-(3-bromobenzyl)-2,2-dimethoxyacetamide; With sulfuric acid; at 40 ℃; for 16h;

With sodium hydroxide; water; at 0 ℃; pH=7 - 8;

Reference yield:

7-bromoisoquinolin-3-ol (662139-46-0) + 4-(bromomethyl)benzoic acid 1,1-dimethylethyl ester (108052-76-2) → 4-(7-bromo-3-oxo-2H-isoquinolin-2-ylmethyl)benzoic acid tert-butyl ester (662139-45-9)

Guidance literature:

With caesium carbonate; In DMF (N,N-dimethyl-formamide); at 20 ℃;

Reference yield:

7-bromoisoquinolin-3-ol (662139-46-0) + p-methoxybenzyl chloride (824-94-2) → 7-bromo-2-[(4-methoxyphenyl)methyl]-2,3-dihydroisoquinolin-3-one

Guidance literature:

With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

upstream raw materials:

N-(3-bromobenzyl)-2,2-dimethoxyacetamide

Downstream raw materials:

4-(7-bromo-3-oxo-2H-isoquinolin-2-ylmethyl)benzoic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 662139-46-0 7-Bromo-3-hydroxyisoquinoline

Send

Send

Metric Ton KG G Pound L ML

Send

Send