N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine

Base Information

• Chemical Name: N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine
• CAS No.: 66582-27-2
• Molecular Formula: C22H32N2O3
• Molecular Weight: 372.508
• DSSTox Substance ID: DTXSID70562706
• Wikidata: Q82446965
• Mol file: 66582-27-2.mol

Synonyms:66582-27-2;N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine;N-benzyl-2-[2-[2-[2-(benzylamino)ethoxy]ethoxy]ethoxy]ethanamine;SCHEMBL11179375;DTXSID70562706;1,15-DIPHENYL-5,8,11-TRIOXA-2,14-DIAZAPENTADECANE;D87659;N-Benzyl-1-phenyl-5,8,11-trioxa-2-azatridecan-13-amine

Chemical Property of N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine

Chemical Property:

• XLogP3: 1.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 16
• Exact Mass: 372.24129289
• Heavy Atom Count: 27
• Complexity: 289

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CNCCOCCOCCOCCNCC2=CC=CC=C2

Technology Process of N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine

There total 1 articles about N-benzyl-2-(2-(2-(2-(benzylamino)ethoxy)ethoxy)ethoxy)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

1,11-dichloro-3,6,9-trioxaundecane (638-56-2,27252-69-3) + benzylamine (100-46-9) → 1,15-Diphenyl-5,8,11-trioxa-2,14-diazapentadecane (66582-27-2)

Guidance literature:

With sodium carbonate; In toluene; for 20h; Heating;

DOI:10.1021/jo00297a068

Reference yield: 75.0%

1,15-Diphenyl-5,8,11-trioxa-2,14-diazapentadecane (66582-27-2) + chloroacetyl chloride (79-04-9) → N-Benzyl-N-{2-[2-(2-{2-[benzyl-(2-chloro-acetyl)-amino]-ethoxy}-ethoxy)-ethoxy]-ethyl}-2-chloro-acetamide (126111-89-5)

Guidance literature:

With potassium carbonate; In chloroform; water; for 2h; Ambient temperature;

DOI:10.1021/jo00297a068

Reference yield: 60.0%

1,15-Diphenyl-5,8,11-trioxa-2,14-diazapentadecane (66582-27-2) + (4-Chlorocarbonylmethoxy-butoxy)-acetyl chloride → 9,21-dibenzyl-9,21-diaza-1,6,12,15,18-pentaoxacyclotricosane-8,22-dione (87674-26-8)

Guidance literature:

In benzene;

upstream raw materials:

1,11-dichloro-3,6,9-trioxaundecane

benzylamine

Downstream raw materials:

7,19-dibenzyl-2,3-dimethyl-7,19-diaza-1,4,10,13,16-pentaoxacyclopentadecane-6,20-dione

8,20-dibenzyl-3,3-dimethyl-8,20-diaza-1,5,11,14,17-pentaoxacyclodocosane-7,21-dione

8,20-dibenzyl-8,20-diaza-1,5,11,14,17-pentaoxacyclodocosane-7,21-dione

9,21-dibenzyl-9,21-diaza-1,6,12,15,18-pentaoxacyclotricosane-8,22-dione