4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-

Base Information

Chemical Name:4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-
CAS No.:670223-05-9
Molecular Formula:C13H23NOS
Molecular Weight:241.398
Hs Code.:
DSSTox Substance ID:DTXSID60460944
Nikkaji Number:J2.020.650K
Wikidata:Q82285134

Synonyms:4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-;670223-05-9;DTXSID60460944

Suppliers and Price of 4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-

Chemical Property:

XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:241.15003553
Heavy Atom Count:16
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C(CC=C)SC1CCCCC1
Isomeric SMILES:CN(C)C(=O)[C@H](CC=C)SC1CCCCC1

Technology Process of 4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)-

There total 3 articles about 4-Pentenamide, 2-(cyclohexylthio)-N,N-dimethyl-, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 670223-06-0
(SS,2S)-2-cyclohexylsulfinyl-N,N-dimethylpent-4-enamide

: 670223-05-9
(S)-2-cyclohexylsulfanyl-N,N-dimethylpent-4-enamide

Guidance literature:: With tetraphosphorus decasulfide; In dichloromethane; at 20 ℃; for 0.75h;
DOI:10.1021/jo035488b

Reference yield:

: 385837-48-9
(SS,2S)-2-cyclohexylsulfinyl-N,N-dimethylpent-4-enethioamide

: 670223-05-9
(S)-2-cyclohexylsulfanyl-N,N-dimethylpent-4-enamide

Guidance literature:: Multi-step reaction with 2 steps

1: dimethyldioxirane

2: 90 percent / P₄S₁₀ / CH₂Cl₂ / 20 °C

With tetraphosphorus decasulfide; 3,3-dimethyldioxirane; In dichloromethane;
DOI:10.1002/ejoc.200500884

Reference yield:

: 226709-30-4
(R)-2-(Cyclohexylsulfinyl)-N,N-dimethylethanethioamide

: 670223-05-9
(S)-2-cyclohexylsulfanyl-N,N-dimethylpent-4-enamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: tBuLi / tetrahydrofuran / -40 °C

1.2: tetrahydrofuran

1.3: CeCl₃ / tetrahydrofuran / 20 h / 20 °C

2.1: dimethyldioxirane

3.1: 90 percent / P₄S₁₀ / CH₂Cl₂ / 20 °C

With tetraphosphorus decasulfide; tert.-butyl lithium; 3,3-dimethyldioxirane; In tetrahydrofuran; dichloromethane; 1.3: thio-Claisen transposition reaction;
DOI:10.1002/ejoc.200500884