1-(6-Phenylpyrimidin-4-yl)propan-1-one

Base Information

Chemical Name:1-(6-Phenylpyrimidin-4-yl)propan-1-one
CAS No.:67073-98-7
Molecular Formula:C13H12N2O
Molecular Weight:212.251
Hs Code.:
DSSTox Substance ID:DTXSID40497152
Wikidata:Q82346553

Synonyms:1-(6-Phenylpyrimidin-4-yl)propan-1-one;67073-98-7;DTXSID40497152

Suppliers and Price of 1-(6-Phenylpyrimidin-4-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 1-(6-Phenylpyrimidin-4-yl)propan-1-one

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:212.094963011
Heavy Atom Count:16
Complexity:236

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)C1=NC=NC(=C1)C2=CC=CC=C2

Technology Process of 1-(6-Phenylpyrimidin-4-yl)propan-1-one

There total 7 articles about 1-(6-Phenylpyrimidin-4-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 89967-12-4
1-(6-Phenyl-pyrimidin-4-yl)-propan-1-one oxime

: 67073-98-7
6-phenyl-4-propionylpyrimidine

Guidance literature:: With hydrogenchloride; 2-oxo-propionic acid; In ethanol; for 6h; Heating;

Reference yield: 51.0%

: 3438-48-0
4-phenylpyrimidine

: 123-38-6
propionaldehyde

: 67073-98-7
6-phenyl-4-propionylpyrimidine

Guidance literature:: With tert.-butylhydroperoxide; iron(II) sulfate; In water; at 10 - 20 ℃; for 0.25h;
DOI:10.1248/cpb.28.571

Reference yield:

: 5331-13-5
1-phenyl-1,3-hexanedione

: 67073-98-7
6-phenyl-4-propionylpyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: 64 percent / conc. HCl / ethanol / 48 h / Heating

2: 94 percent / phosphoryl chloride / 3 h / Heating

3: 96 percent / hydrogen/conc. ammonia / 5percent palladium charcoal / methanol

4: 75 percent / propyl nitrite, HCl / ethanol / 2 h / Ambient temperature

5: 66 percent / pyruvic acid, conc. HCl / aq. ethanol / 6 h / Heating

With hydrogenchloride; ammonium hydroxide; n-propyl nitrite; hydrogen; 2-oxo-propionic acid; trichlorophosphate; palladium on activated charcoal; In methanol; ethanol;