1,7-Dimethylindolin-2-one

Base Information

Chemical Name:1,7-Dimethylindolin-2-one
CAS No.:67358-21-8
Molecular Formula:C10H11NO
Molecular Weight:161.203
Hs Code.:
DSSTox Substance ID:DTXSID00565386
Nikkaji Number:J3.123.892G
Wikidata:Q82450453

Synonyms:1,7-Dimethylindolin-2-one;67358-21-8;2H-Indol-2-one, 1,3-dihydro-1,7-dimethyl-;1,7-dimethyl-2,3-dihydro-1H-indol-2-one;SCHEMBL11630037;DTXSID00565386;MFCD26620541;1,7-DIMETHYL-3H-INDOL-2-ONE;BS-46041;1,7-Dimethyl-1,3-dihydro-2H-indol-2-one;E79882

Suppliers and Price of 1,7-Dimethylindolin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 1,7-Dimethylindolin-2-one

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:161.084063974
Heavy Atom Count:12
Complexity:202

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)CC(=O)N2C

Technology Process of 1,7-Dimethylindolin-2-one

There total 14 articles about 1,7-Dimethylindolin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 27237-52-1
N-methyl-N-2,6-dimethylphenylcarbamoylchloride

: 67358-21-8
1,7-dimethylindolin-2-one

: 767-71-5
N-methyl-2,6-dimethylaniline

Guidance literature:: With N-hydroxy pivalamide; carbon monoxide; palladium diacetate; caesium carbonate; catacxium A; In 1,3,5-trimethyl-benzene; at 120 ℃; for 3h; chemoselective reaction;
DOI:10.1002/anie.201108889

Reference yield: 86.0%

: 13508-78-6
N-methyl-2-methylchloroacetanilide

: 67358-21-8
1,7-dimethylindolin-2-one

Guidance literature:: With palladium diacetate; triethylamine; johnphos; In toluene; at 80 ℃; for 6h;
DOI:10.1021/ja037546g

Reference yield:

: 156267-16-2
benzyl N-(2,6-dimethylphenyl)carbamate

: 67358-21-8
1,7-dimethylindolin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) THF, 2.) THF, 20 deg C, 30 min

2: hydrogen / Pd/C / methanol

3: 1.) n-butyllithium, 3.) n-butyllithium, 5.) 0.1 M HCl

With hydrogenchloride; n-butyllithium; hydrogen; sodium hydride; palladium on activated charcoal; In methanol;
DOI:10.1021/jm00039a016