N(7)-hydroxyethylguanine

Base Information

Chemical Name:N(7)-hydroxyethylguanine
CAS No.:53498-52-5
Molecular Formula:C7H9 N5 O2
Molecular Weight:195.18
Hs Code.:
Mol file:53498-52-5.mol

Synonyms:Guanine,7-(2-hydroxyethyl)- (7CI); 7-(2-Hydroxyethyl)guanine; 7-(b-Hydroxyethyl)guanine;N7-(2-Hydroxyethyl)guanine; NSC 637506

Suppliers and Price of N(7)-hydroxyethylguanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N7-(2-Hydroxyethyl)guanine
100mg
$ 140.00

American Custom Chemicals Corporation
2-AMINO-1,7-DIHYDRO-7-(2-HYDROXYETHYL)-6H-PURIN-6-ONE 95.00%
5MG
$ 503.12

AccelPharmtech
2-amino-1,7-dihydro-7-(2-hydroxyethyl)-6H-Purin-6-one 97.00%
25G
$ 3120.00

AccelPharmtech
2-amino-1,7-dihydro-7-(2-hydroxyethyl)-6H-Purin-6-one 97.00%
1G
$ 1530.00

Total 5 raw suppliers

Chemical Property of N(7)-hydroxyethylguanine

Chemical Property:

Vapor Pressure:1.71E-14mmHg at 25°C
Melting Point:>300°C
Boiling Point:584.3°C at 760 mmHg
Flash Point:307.1°C
PSA：109.82000
Density:1.86g/cm³
LogP:-0.72470
Storage Temp.:Refrigerator

Purity/Quality:

97% ^*data from raw suppliers

N7-(2-Hydroxyethyl)guanine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An ethylene oxide-DNA adduct ss.

Technology Process of N(7)-hydroxyethylguanine

There total 3 articles about N(7)-hydroxyethylguanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75-21-8,99932-75-9
oxirane

: 118-00-3
G

: 53498-52-5
2-amino-7-(2-hydroxyethyl)purin-6-one

Guidance literature:: With acetic acid; Yield given. Multistep reaction; 1.) 6 h, 2.) H₂O, 80 to 100 deg C, 2 h;
DOI:10.1021/jo00029a008

Reference yield:

: 550346-48-0
α-hydroperoxy-N-nitrosomorpholine

: 961-07-9
2'-Deoxyguanosine

: 53498-52-5
2-amino-7-(2-hydroxyethyl)purin-6-one

: 78014-96-7
O⁶-(2-Hydroxyethyl)guanine

Guidance literature:: α-hydroperoxy-N-nitrosomorpholine; 2'-Deoxyguanosine; With tris-(2-carboxyethyl)-phosphine hydrochloride; In acetonitrile; at 23 ℃; for 0.00277778h; aq. buffer;

With hydrogenchloride; In water; acetonitrile; at 80 ℃; for 0.5h;

With sodium hydroxide; In water; acetonitrile; pH=7; pH-value; Kinetics;
DOI:10.1021/tx100093a