Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-

Base Information

Chemical Name:Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-
CAS No.:102583-95-9
Molecular Formula:C₁₄H₉ClF₃NO₂
Molecular Weight:315.679
Hs Code.:
Mol file:102583-95-9.mol

Synonyms:Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-

Suppliers and Price of Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[[3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO]BENZOIC ACID 95.00%
5MG
$ 500.13

Total 1 raw suppliers

Chemical Property of Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-

Chemical Property:

Vapor Pressure:2.37E-06mmHg at 25°C
Boiling Point:376.9°Cat760mmHg
Flash Point:181.8°C
PSA：49.33000
Density:1.478g/cm³
LogP:4.87360

Purity/Quality:: 2-[[3-CHLORO-5-(TRIFLUOROMETHYL)PHENYL]AMINO]BENZOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]-

There total 2 articles about Benzoic acid, 2-[[3-chloro-5-(trifluoromethyl)phenyl]amino]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: N-(3-chloro-5-(trifluoromethyl)phenyl)anthranilic acid

: 102583-95-9
N-(3-chloro-5-(trifluoromethyl)phenyl)anthranilic acid

Guidance literature:: N-(3-chloro-5-(trifluoromethyl)phenyl)anthranilic acid; With lithium hydroxide; In 1,4-dioxane; water; at 80 ℃; for 4h;

With hydrogenchloride; In 1,4-dioxane; water;
DOI:10.1021/jm401061w

Reference yield:

: 610-94-6
2-bromobenzoic acid methyl ester

: 69411-05-8
3-chloro-5-(trifluoromethyl)phenylaniline

: 102583-95-9
N-(3-chloro-5-(trifluoromethyl)phenyl)anthranilic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾ / toluene / 120 °C / Inert atmosphere; Reflux

2: lithium hydroxide / 1,4-dioxane; water / 4 h / 80 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; lithium hydroxide; In 1,4-dioxane; water; toluene; 1: |Buchwald-Hartwig Coupling;
DOI:10.1021/jm401061w