Technology Process of 3,6,9,12,15-Pentaoxaheptadecanoic acid,
17-[4-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]phenoxy]
-, 1,1-dimethylethyl ester
There total 9 articles about 3,6,9,12,15-Pentaoxaheptadecanoic acid,
17-[4-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]phenoxy]
-, 1,1-dimethylethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 88 percent / carbon tetrabromide; triphenylphosphine / CH2Cl2 / 1 h / 20 °C
2: 84 percent / NaH / tetrahydrofuran / 2.33 h / 0 - 20 °C
3: 85 percent / trifluoroacetic acid / CH2Cl2; H2O / 2.5 h / 20 °C
4: 68 percent / NaH / tetrahydrofuran; dimethylformamide / 2 h / 20 °C
5: 575 mg / H2 / Pd(OH)2-C / methanol / 4 h / 20 °C
With
carbon tetrabromide; hydrogen; sodium hydride; triphenylphosphine; trifluoroacetic acid;
palladium hydroxide - carbon;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.03.052
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 32 percent / potassium hydroxide / 2 h / 130 °C
2: 88 percent / carbon tetrabromide; triphenylphosphine / CH2Cl2 / 1 h / 20 °C
3: 84 percent / NaH / tetrahydrofuran / 2.33 h / 0 - 20 °C
4: 85 percent / trifluoroacetic acid / CH2Cl2; H2O / 2.5 h / 20 °C
5: 68 percent / NaH / tetrahydrofuran; dimethylformamide / 2 h / 20 °C
6: 575 mg / H2 / Pd(OH)2-C / methanol / 4 h / 20 °C
With
potassium hydroxide; carbon tetrabromide; hydrogen; sodium hydride; triphenylphosphine; trifluoroacetic acid;
palladium hydroxide - carbon;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2004.03.052
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 60 percent / tributylphosphine; 1,1'-azo-bis-N,N'-dimethylformamide / toluene / 20 °C
2: 85 percent / TBAF / tetrahydrofuran / 0.17 h / 20 °C
3: 84 percent / NaH / tetrahydrofuran / 2.33 h / 0 - 20 °C
4: 85 percent / trifluoroacetic acid / CH2Cl2; H2O / 2.5 h / 20 °C
5: 68 percent / NaH / tetrahydrofuran; dimethylformamide / 2 h / 20 °C
6: 575 mg / H2 / Pd(OH)2-C / methanol / 4 h / 20 °C
With
tributylphosphine; diamide; tetrabutyl ammonium fluoride; hydrogen; sodium hydride; trifluoroacetic acid;
palladium hydroxide - carbon;
In
tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene;
1: Mitsunobu reaction;
DOI:10.1016/j.bmc.2004.03.052
![2-(2-{2-[2-(2-benzyloxyethoxy)ethoxy]ethoxy}ethoxy)ethanol](/Databaselist/images/loading.webp)
