4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester

Base Information

Chemical Name:4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester
CAS No.:67618-38-6
Molecular Formula:C13H13N3O2S
Molecular Weight:275.331
Hs Code.:
DSSTox Substance ID:DTXSID10382667

Synonyms:67618-38-6;4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester;DTXSID10382667;benzylidenehydrazino-4-ethoxycarbonylthiazole

Suppliers and Price of 4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:275.07284784
Heavy Atom Count:19
Complexity:319

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CSC(=N1)NN=CC2=CC=CC=C2

Technology Process of 4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester

There total 6 articles about 4-Thiazolecarboxylic acid, 2-[(phenylmethylene)hydrazino]-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1627-73-2
1-benzylidene thiosemicarbazide

: 65868-37-3
ethyl 2-oxo-3-chloropropionate

: 67618-38-6
2-benzylidenehydrazino-4-ethoxycarbonylthiazole

Guidance literature:: In 1,4-dioxane; at 65 ℃; for 0.5h;
DOI:10.1007/BF00480845

Reference yield: 83.0%

: 70-23-5
ethyl Bromopyruvate

: 100-52-7
benzaldehyde

: 79-19-6
thiosemicarbazide

: 67618-38-6
2-benzylidenehydrazino-4-ethoxycarbonylthiazole

Guidance literature:: In ethanol; for 0.5h; Heating;

Reference yield:

: 70-23-5
ethyl Bromopyruvate

: 67618-38-6
2-benzylidenehydrazino-4-ethoxycarbonylthiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 47 percent / conc. HCl / 0.17 h / 0 °C

2: conc. HCl / H₂O; ethanol / Heating

With hydrogenchloride; In ethanol; water;
DOI:10.1007/BF00480848