2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-

Base Information

Chemical Name:2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-
CAS No.:678195-43-2
Molecular Formula:C16H12O2
Molecular Weight:236.27
Hs Code.:
DSSTox Substance ID:DTXSID60458765
Nikkaji Number:J2.662.701J

Synonyms:2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-;678195-43-2;DTXSID60458765;1,2-Diphenyl-2-cyclopropene-1-carboxylic acid

Suppliers and Price of 2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:236.083729621
Heavy Atom Count:18
Complexity:359

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC2(C3=CC=CC=C3)C(=O)O

Technology Process of 2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl-

There total 4 articles about 2-Cyclopropene-1-carboxylic acid, 1,2-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 678195-39-6
methyl 1,2-diphenylcycloprop-2-ene-1-carboxylate

: 678195-43-2
(+/-)-1,2-diphenylcycloprop-2-ene-1-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; water; at 35 ℃;
DOI:10.1016/j.tet.2003.12.042

Reference yield: 81.0%

: 591-50-4
iodobenzene

: 824425-20-9
1-phenylcycloprop-2-ene-1-carboxylic acid

: 678195-43-2
(+/-)-1,2-diphenylcycloprop-2-ene-1-carboxylic acid

Guidance literature:: 1-phenylcycloprop-2-ene-1-carboxylic acid; With methyllithium; In tetrahydrofuran; diethyl ether; at -78 - -40 ℃; for 0.2h;

With zinc(II) chloride; In tetrahydrofuran; diethyl ether; at -78 ℃; for 0.0833333h;

iodobenzene; Further stages;
DOI:10.1021/jo801683n

Reference yield:

: 22979-35-7
Methyl phenyldiazoacetate

: 678195-43-2
(+/-)-1,2-diphenylcycloprop-2-ene-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / Rh₂(OAc)4 / CH₂Cl₂ / 20 °C

2: 91 percent / KOH / methanol; H₂O / 35 °C

With potassium hydroxide; dirhodium tetraacetate; In methanol; dichloromethane; water;
DOI:10.1016/j.tet.2003.12.042