1,1-Difluoro-2-methylenecyclopropane

Base Information

• Chemical Name: 1,1-Difluoro-2-methylenecyclopropane
• CAS No.: 67884-63-3
• Molecular Formula: C4H4F2
• Molecular Weight: 90.0726
• DSSTox Substance ID: DTXSID20503609
• Nikkaji Number: J1.245.272A
• Mol file: 67884-63-3.mol

Synonyms:1,1-Difluoro-2-methylenecyclopropane;67884-63-3;1,1-Difluoro-2-methylidenecyclopropane;LXYBTFPYXKJLAS-UHFFFAOYSA-;DTXSID20503609;LXYBTFPYXKJLAS-UHFFFAOYSA-N;YTXPGYPUGLGROC-UHFFFAOYSA-N;InChI=1/C4H4F2/c1-3-2-4(3,5)6/h1-2H2

Chemical Property of 1,1-Difluoro-2-methylenecyclopropane

Chemical Property:

• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 90.02810645
• Heavy Atom Count: 6
• Complexity: 93.7

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=C1CC1(F)F

Technology Process of 1,1-Difluoro-2-methylenecyclopropane

There total 3 articles about 1,1-Difluoro-2-methylenecyclopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

Hexafluoropropene oxide (428-59-1,25038-02-2) + 1,2-propanediene (463-49-0) → trifluoroacetyl fluoride (354-34-7) + 1-(difluoromethylene)cyclopropane (67884-64-4) + 1,1-difluoro-2-methylenecyclopropane (67884-63-3) + 1,1,2,2-Tetrafluorospiropentane (76178-55-7)

Guidance literature:

at 180 ℃; for 6h; vacuo;

DOI:10.1016/S0022-1139(00)85226-4

Reference yield: 36.0%

1,2-propanediene (463-49-0) + trimethyl(trifluoromethyl)tin (754-25-6) → polytetrafluoroethylene (116-14-3,82785-14-6) + 1,1-difluoro-2-methylenecyclopropane (67884-63-3)

Guidance literature:

at 150 ℃; for 3h; silica tube in vacuo;

DOI:10.1016/S0022-1139(00)85225-2

Reference yield:

4-(difluoromethylene)-4,5-dihydro-3H-pyrazole (88766-66-9) → 1,2-propanediene (463-49-0) + 1-(difluoromethylene)cyclopropane (67884-64-4) + 1,1-difluoro-2-methylenecyclopropane (67884-63-3)

Guidance literature:

at 38 ℃; for 0.5h; under 2 - 660 Torr; Product distribution; Mechanism; Irradiation; also with added argon and in CCl₄ solution; var. time;

DOI:10.1021/ja00319a038

upstream raw materials:

Hexafluoropropene oxide

1,2-propanediene

trimethyl(trifluoromethyl)tin

4-(difluoromethylene)-4,5-dihydro-3H-pyrazole

Downstream raw materials:

1,1-difluoro-4,4-diphenylspiropentane

1,1-difluoro-6,6-diphenyl-4,5-diazaspiro<2.4>hept-4-ene