Hexafluoropropylene oxide

Base Information

• Chemical Name: Hexafluoropropylene oxide
• CAS No.: 428-59-1
• Deprecated CAS: 75579-38-3
• Molecular Formula: C3F6O
• Molecular Weight: 166.023
• Hs Code.: 2910900090
• European Community (EC) Number: 207-050-4,626-882-2
• UN Number: 1956
• UNII: JPY12AP87N
• DSSTox Substance ID: DTXSID6029177
• Nikkaji Number: J27.198E
• Wikipedia: Hexafluoropropylene_oxide
• Wikidata: Q2693924
• Mol file: 428-59-1.mol

Synonyms:2,2,3-trifluoro-3-(trifluoromethyl)oxirane;2,3,3,3-Tetrafluoro-2-(1,1,2,2,3,3,3,heptafluoropropoxy)propanoic acid;2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoic acid;2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate;2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid;2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propionic acid;ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate;ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate;ammonium 2-(perfluoropropoxy)perfluoropropionate;ammonium perfluoro(2-methyl-3-oxahexanoic) acid;ammonium perfluoro-2-methyl-3-oxahexanoate;azanium;2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)propanoate;C6HF11O3.H3N;GenX ammonium perfluoro-2-methyl-3-oxahexanoate;GenX perfluoro(2-propoxypropanoate);GenX perfluoro-2-methyl-3-oxahexanoic acid;GenX potassium salt;GenX-K;GenX-Na;hexafluoroepoxypropane;hexafluoropropene oxide;hexafluoropropylene oxide;hexafluoropropylene oxide dimer acid;hexafluoropropylene oxide tetramer acid;hexafluoropropylene oxide trimer acid;HFPO hexafluoropropylene oxide;HFPO-DA;HFPO-DA hexafluoropropylene oxide dimer acid;HFPO-TA;HFPO-TA hexafluoropropylene oxide trimer acid;HFPO-TeA;HFPO-TeA hexafluoropropylene oxide tetramer acid;HFPO-TrA;HFPO-TrA hexafluoropropylene oxide trimer acid;HFPO2 compound;per- and polyfluoroalkyl ether acids;perfluoro(2-propoxypropanoate);perfluoro-2-(propyloxy)propionic acid;perfluoro-2-methyl-3-oxahexanoic acid;perfluoro-2-propoxypropanoic acid;perfluoro-2-propoxypropionic acid;PFEA per- and polyfluoroalkyl ether acids;potassium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate;propanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-, potassium salt (1:1);propanoic acid, 2,3,3,3-tetrafluoro-2-(1,1,2,2,3,3,3-heptafluoropropoxy)-, sodium salt (1:1);sodium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate

Chemical Property of Hexafluoropropylene oxide

Chemical Property:

• Appearance/Colour: colorless odorless gas
• Vapor Pressure: 680.85kPa at 25℃
• Melting Point: -129 °C
• Boiling Point: -42 °C
• PSA: 12.53000
• Density: 1.67 g/cm³
• LogP: 1.83750
• Water Solubility.: 16.3μg/L at 22.7℃
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 0
• Exact Mass: 165.98533359
• Heavy Atom Count: 10
• Complexity: 161
• Transport DOT Label: Non-Flammable Gas

Purity/Quality:

99.9% ^*data from raw suppliers

Hexafluoropropene oxide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38-44
• Safety Statements: 7-26-37/39-38

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Other Monomers
• Canonical SMILES: C1(C(O1)(F)F)(C(F)(F)F)F
• Uses: Hexafluoropropylene oxide is an important intermediate of organic fluorine material.HFPO is mainly used in the manufacture of high-quality fluorinated compounds.It is the main component of perfluor-vinyl ether(PPVE,PSVE,PFVE,PMVE) and the monomer of fluorinated surfactants and fluorinated ether oil.

Technology Process of Hexafluoropropylene oxide

There total 15 articles about Hexafluoropropylene oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) → Hexafluoropropene oxide (428-59-1,25038-02-2)

Guidance literature:

With 1-pyrrolidone; In 1,1,2-Trichloro-1,2,2-trifluoroethane; N,N-dimethyl-formamide; at 20 ℃; for 6h; Reagent/catalyst; Temperature; Solvent; Sealed tube;

Reference yield: 62.0%

perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) → polytetrafluoroethylene (116-14-3,82785-14-6) + Hexafluoropropene oxide (428-59-1,25038-02-2) + trifluoroacetyl fluoride (354-34-7) + 1,1,2,2,3,3-Hexafluoro-cyclopropane (931-91-9)

Guidance literature:

With oxygen; In tetrachloromethane; at 155 ℃; for 3h;

DOI:10.1021/op900151p

Reference yield: 51.0%

perfluoropropylene (116-15-4,13429-24-8,25120-07-4,6792-31-0) → Hexafluoropropene oxide (428-59-1,25038-02-2) + freon-218 (76-19-7) + C3F12OSe + C3F16O2Se2

Guidance literature:

With xenon bis-pentafluoroseleniumoxide; at 65 ℃; for 84h;

DOI:10.1016/S0022-1139(00)82774-8

upstream raw materials:

epichlorohydrin

perfluoropropylene

difluorodioxirane

perfluoro(propyl vinyl ether)

Downstream raw materials:

2-fluoro-2-methoxy trifluoropropanoic acid methyl ester

ethyl Pentafluoropropionate

α-Chlor-perfluorpropionsaeure-aethylester

2-bromo-2,3,3,3-tetrafluoropropionic acid ethyl ester

Refernces

Methyl 2-methoxytetrafluoropropionate as a synthetic equivalent of methyl trifluoropyruvate in the Claisen condensation. The first synthesis of 2-(trifluoroacetyl)chromones and 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones

10.1016/j.tetlet.2009.06.067

The research focuses on the development of a novel synthetic method for the preparation of 2-(trifluoroacetyl)chromones and 5-aryl-2-hydroxy-2-(trifluoromethyl)furan-3(2H)-ones. The study utilizes methyl 2-methoxytetrafluoropropionate as a key reagent, which is easily prepared from hexafluoropropene epoxide and methanol. This compound serves as a stable and effective equivalent of methyl trifluoropyruvate in the Claisen condensation with various acetophenones, yielding intermediates that are subsequently deprotected using sulfuric acid to obtain the desired products. The synthesized compounds exhibit unique physical and biological properties due to the presence of the trifluoromethyl group, making them valuable precursors for the construction of more complex trifluoromethylated heterocycles. The research highlights the practicality and efficiency of this approach, demonstrating its potential for further synthetic applications in the field of organic chemistry.

OPTICALLY ACTIVE PERFLUORO-2-PROPOXYPROPIONIC ACID

10.1246/cl.1980.843

The research focuses on the synthesis and characterization of optically active perfluoro-2-propoxypropionic acid. The key chemicals involved include perfluoro-2-propoxypropionyl fluoride, which was prepared by the anionic dimerization of perfluoro-1,2-epoxypropane using tetramethylurea in diglyme. This fluoride reacted with (-)-1-phenylethylamine to form a mixture of diastereomeric amides. These amides were separated chromatographically, and their subsequent hydrolysis yielded the enantiomers of perfluoro-2-propoxypropionic acid, marking the first example of optically active organic perfluoro compounds. The study highlights the potential of these compounds as reagents for analyzing enantiomers and as solvents for 1H NMR analysis of chiral molecules, given their stability and lack of hydrogen atoms.

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 428-59-1 Hexafluoropropylene oxide

Send

Send

Metric Ton KG G Pound L ML

Send

Send