2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde

Base Information

Chemical Name:2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde
CAS No.:68236-25-9
Molecular Formula:C13H12ClNO4
Molecular Weight:281.696
Hs Code.:2933499090
European Community (EC) Number:673-317-0
DSSTox Substance ID:DTXSID40355965
Wikidata:Q82135066
Mol file:68236-25-9.mol

Synonyms:2-chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde;68236-25-9;2-chloro-5,6,7-trimethoxy-3-quinolinecarbaldehyde;2-Chloro-5,6,7-trimethoxy-quinoline-3-carbaldehyde;Oprea1_445957;Oprea1_519224;SCHEMBL9243890;DTXSID40355965;MFCD02224032;AKOS000617644;SB69640;BS-36420;CS-0322647;AG-690/15443858;SR-01000310651;SR-01000310651-1;2-Chloro-5,6,7-trimethoxy-3-quinolinecarbaldehyde, AldrichCPR

Suppliers and Price of 2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde 95+%
1g
$ 522.00

Chemenu
2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde 95%
1g
$ 493.00

ChemBridge Corporation
2-chloro-5,6,7-trimethoxy-3-quinolinecarbaldehyde 95%
200 μmol
$ 35.00

American Custom Chemicals Corporation
2-CHLORO-5,6,7-TRIMETHOXY-QUINOLINE-3-CARBALDEHYDE 95.00%
1G
$ 1280.66

Total 6 raw suppliers

Chemical Property of 2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde

Chemical Property:

Vapor Pressure:3.26E-07mmHg at 25°C
Boiling Point:418.5oC at 760 mmHg
Flash Point:206.9oC
PSA：57.65000
Density:1.326g/cm3
LogP:2.72650
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:281.0454856
Heavy Atom Count:19
Complexity:317

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C2C=C(C(=NC2=C1)Cl)C=O)OC)OC

Technology Process of 2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde

There total 3 articles about 2-Chloro-5,6,7-trimethoxyquinoline-3-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 4304-24-9
N-(3,4,5-trimethoxyphenyl)acetamide

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 68236-25-9
2-chloro-5,6,7-trimethoxyquinoline-3-carboxaldehyde

Guidance literature:: With trichlorophosphate; for 1.5h; Heating;
DOI:10.1039/P19810001520

Reference yield:

: 24313-88-0
3,4,5-Trimethoxyaniline

: 68236-25-9
2-chloro-5,6,7-trimethoxyquinoline-3-carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 0 - 5 °C

2: trichlorophosphate / 0 - 90 °C

With trichlorophosphate; 2: |Vilsmeier-Haack Formylation;
DOI:10.1016/j.molstruc.2019.127310