N-(3,4,5-Trimethoxyphenyl)acetamide

Base Information

Chemical Name:N-(3,4,5-Trimethoxyphenyl)acetamide
CAS No.:4304-24-9
Molecular Formula:C11H15NO4
Molecular Weight:225.244
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50195652
Nikkaji Number:J1.402.673H
Wikidata:Q83068670
ChEMBL ID:CHEMBL1097277
Mol file:4304-24-9.mol

Synonyms:N-(3,4,5-Trimethoxyphenyl)acetamide;4304-24-9;Acetanilide, 3',4',5'-trimethoxy-;BRN 2853730;3',4',5'-Trimethoxyacetanilide;Acetamide, N-(3,4,5-trimethoxyphenyl)-;4-13-00-02908 (Beilstein Handbook Reference);TimTec1_002677;Oprea1_102732;SCHEMBL6796229;CHEMBL1097277;DTXSID50195652;3',4',5'-Trimethoxyacetoanilide;HMS1541J15;STK218259;5-Acetamido-1,2,3-trimethoxybenzene;AKOS001326619;N-(3,4,5-Trimethoxyphenyl)acetamide #;NCGC00173863-01;N~1~-(3,4,5-trimethoxyphenyl)acetamide;CS-0237114;EN300-178121;SR-01000529487;SR-01000529487-1;Z28259401

Suppliers and Price of N-(3,4,5-Trimethoxyphenyl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(3,4,5-trimethoxyphenyl)acetamide
250mg
$ 220.00

American Custom Chemicals Corporation
N-(3,4,5-TRIMETHOXYPHENYL)ACETAMIDE 95.00%
5MG
$ 502.10

Total 5 raw suppliers

Chemical Property of N-(3,4,5-Trimethoxyphenyl)acetamide

Chemical Property:

Vapor Pressure:5.5E-06mmHg at 25°C
Boiling Point:380.3°C at 760 mmHg
Flash Point:183.8°C
PSA：60.28000
Density:1.157g/cm³
LogP:2.32030
XLogP3:1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:225.10010796
Heavy Atom Count:16
Complexity:220

Purity/Quality:

95% ^*data from raw suppliers

N-(3,4,5-trimethoxyphenyl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC(=C(C(=C1)OC)OC)OC

Technology Process of N-(3,4,5-Trimethoxyphenyl)acetamide

There total 6 articles about N-(3,4,5-Trimethoxyphenyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 108-24-7
acetic anhydride

: 24313-88-0
3,4,5-Trimethoxyaniline

: 4304-24-9
N-(3,4,5-trimethoxyphenyl)acetamide

Guidance literature:: With pyridine; Ambient temperature;
DOI:10.1002/jhet.5570330665

Reference yield: 74.0%

: 24313-88-0
3,4,5-Trimethoxyaniline

: 105-53-3
diethyl malonate

: 4304-24-9
N-(3,4,5-trimethoxyphenyl)acetamide

Guidance literature:: 3,4,5-Trimethoxyaniline; diethyl malonate; at 100 - 130 ℃;

With caesium carbonate; In 1,4-dioxane; at 100 ℃;
DOI:10.1080/00397911.2012.717671

Reference yield:

: 3086-62-2
3,4,5-trimethoxybenzamide

: 4304-24-9
N-(3,4,5-trimethoxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: hypochlorite; sodium hydroxide / unter Eiszusatz

2: Acetylierung

With sodium hydroxide; sodium hypochlorite;