(1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID

Base Information

• Chemical Name: (1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID
• CAS No.: 20459-60-3
• Molecular Formula: C5H14 N O3 P
• Molecular Weight: 167.14
• Hs Code.: 29310099
• Mol file: 20459-60-3.mol

Synonyms:Phosphonicacid, (1-amino-3-methylbutyl)- (8CI,9CI); (1-Amino-3-methylbutyl)phosphonicacid; (?à)-(1-Aminoisopentyl)phosphonicacid; DL-(1-Amino-3-methylbutyl)phosphonic acid; NSC 117801

Chemical Property of (1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID

Chemical Property:

• Vapor Pressure: 0.000106mmHg at 25°C
• Melting Point: 274-280 °C
• Boiling Point: 313.7°Cat760mmHg
• Flash Point: 143.5°C
• PSA: 93.36000
• Density: 1.241g/cm³
• LogP: 1.19530

Purity/Quality:

97% ^*data from raw suppliers

(1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 37/39-26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID

There total 1 articles about (1-AMINO-3-METHYLBUTYL)PHOSPHONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid (104513-35-1) → L-1-Amino-3-methylbutylphosphonic acid (20459-60-3,37100-69-9,88081-76-9,88081-77-0) + D-1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid (104513-35-1)

Guidance literature:

With potassium hydroxide; phosphate buffer; In water; for 24h; Ambient temperature; penicillin acylase (EC 3.5.1.11), pH 6.8-7.0;

DOI:10.1016/S0040-4020(01)86439-5

Reference yield: 75.7%

1-Amino-3-methylbutylphosphonic acid (20459-60-3) + phenylacetyl chloride (103-80-0) → 1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid (104513-35-1)

Guidance literature:

With sodium hydrogencarbonate; In water; acetone; 1) -5 deg C, 2 h 2) r.t., 1 h;

DOI:10.1016/S0040-4020(01)86439-5

Reference yield: 73.5%

N-(phenylacetyl)oxysuccinimide (23776-85-4) + 1-Amino-3-methylbutylphosphonic acid (20459-60-3) → 1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid (104513-35-1)

Guidance literature:

With triethylamine; In water; N,N-dimethyl-formamide; 1) 0 deg C, 0.5 h 2) r.t., overnight;

DOI:10.1016/S0040-4020(01)86439-5

upstream raw materials:

1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid

Downstream raw materials:

1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid

D-1-(N-Phenylacetylamino)-3-methylbutylphosphonic acid

Refernces