Benzamide, N-[(4-chlorophenyl)thio]-

Base Information

• Chemical Name: Benzamide, N-[(4-chlorophenyl)thio]-
• CAS No.: 68556-47-8
• Molecular Formula: C13H10ClNOS
• Molecular Weight: 263.748
• DSSTox Substance ID: DTXSID20464125
• Nikkaji Number: J1.385.896I
• Mol file: 68556-47-8.mol

Synonyms:Benzamide, N-[(4-chlorophenyl)thio]-;68556-47-8;DTXSID20464125

Chemical Property of Benzamide, N-[(4-chlorophenyl)thio]-

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 263.0171628
• Heavy Atom Count: 17
• Complexity: 248

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NSC2=CC=C(C=C2)Cl

Technology Process of Benzamide, N-[(4-chlorophenyl)thio]-

There total 6 articles about Benzamide, N-[(4-chlorophenyl)thio]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

benzoyl chloride (98-88-4) + 4-chlorobenzenesulphenamide (73155-25-6) → N-benzoyl-p-chlorobenzenesulfenamide (68556-47-8)

Guidance literature:

With pyridine; In dichloromethane; at -20 ℃; for 0.5h;

DOI:10.1016/S0040-4020(02)01554-5

Reference yield: 84.0%

4,4'-dichlorodiphenyl disulfide (1142-19-4) + benzamide (55-21-0,27208-38-4) → N-benzoyl-p-chlorobenzenesulfenamide (68556-47-8)

Guidance literature:

benzamide; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 1h;

4,4'-dichlorodiphenyl disulfide; In tetrahydrofuran; mineral oil; at 20 ℃; for 36h;

DOI:10.1080/10426507.2015.1012670

Reference yield: 83.0%

4,4'-dichlorodiphenyl disulfide (1142-19-4) + N-chlorobenzamide (1821-34-7) → N-benzoyl-p-chlorobenzenesulfenamide (68556-47-8) + 4-chloro-benzenesulfenyl chloride (933-01-7)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; In benzene; at 20 ℃; for 2h;

upstream raw materials:

C₁₇H₁₇ClN₂O₂S

p-Chlorothiophenol

4,4'-dichlorodiphenyl disulfide

N-chlorobenzamide

Downstream raw materials:

N,N'-dibenzoyl-N-(p-chlorophenylthio)-p-chlorophenylsulfinamidine

benzamidene hydrochloride

4-chloro-benzenesulfenyl chloride

p-chlorobenzene(N-benzoyl)iminosulfinyl chloride