Acetamide, N-(2-hydroxy-5-methoxyphenyl)-

Base Information

Chemical Name:Acetamide, N-(2-hydroxy-5-methoxyphenyl)-
CAS No.:68596-52-1
Molecular Formula:C9H11NO3
Molecular Weight:181.18900
Hs Code.:

Synonyms:2-(acetylamino)-4-methoxyphenol;N-(2-Hydroxy-5-methoxyphenyl)acetamide;2-acetamido-4-methoxyphenol;2-Acetamino-4-methoxy-phenol;acetic acid-(2-hydroxy-5-methoxy-anilide);Essigsaeure-(2-hydroxy-5-methoxy-anilid);N-(2-Hydroxy-5-methoxy-phenyl)-acetamide;

Suppliers and Price of Acetamide, N-(2-hydroxy-5-methoxyphenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 6 raw suppliers

Chemical Property of Acetamide, N-(2-hydroxy-5-methoxyphenyl)-

Chemical Property:

Melting Point:160.6 - 161.5 °C
Boiling Point:387.1±32.0 °C(Predicted)
PSA：58.56000
Density:1.250±0.06 g/cm3(Predicted)
LogP:1.43220

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Acetamide, N-(2-hydroxy-5-methoxyphenyl)-

There total 9 articles about Acetamide, N-(2-hydroxy-5-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 108-24-7
acetic anhydride

: 20734-76-3
2-amino-4-methoxyphenol

: 68596-52-1
N-(2-hydroxy-5-methoxyphenyl)acetamide

Guidance literature:: In water;
DOI:10.1021/jo900267c

Reference yield: 63.0%

: C₉H₁₁NO₃

: 68596-52-1
N-(2-hydroxy-5-methoxyphenyl)acetamide

Guidance literature:: With tris(acetonitrile)(η5-pentamethylcyclopentadienyl)rhodium(III) hexafluoroantimonate; sodium acetate; 5,6,7,8-tetrafluoro-1,2,3,4-tetrahydro-1,4-epoxynaphthalene; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere; Sealed tube; Schlenk technique;
DOI:10.1021/jacs.7b02725

Reference yield:

: 1568-70-3
4-methoxy-2-nitrophenol

: 68596-52-1
N-(2-hydroxy-5-methoxyphenyl)acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / Pd/C / methanol / 24 h

2: 70 °C

With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1002/1099-0690(200206)2002:12<1996::AID-EJOC1996>3.0.CO;2-Q