(E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride

Base Information

Chemical Name:(E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride
CAS No.:113524-39-3
Molecular Formula:C₁₄H₂₁NO*ClH
Molecular Weight:255.788
Hs Code.:
DSSTox Substance ID:DTXSID90921093
Mol file:113524-39-3.mol

Synonyms:Mg 16036;(E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride;113524-39-3;Phenol, 4-(4-(1-aminoethyl)cyclohexyl)-, hydrochloride, (E)-;trans-1-(4-(4-Idrossifenil)cicloesil)etilammina cloridrato [Italian];trans-1-(4-(4-Idrossifenil)cicloesil)etilammina cloridrato;DTXSID90921093;LS-103904;4-[4-(1-Aminoethyl)cyclohexyl]phenol--hydrogen chloride (1/1)

Suppliers and Price of (E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of (E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride

Chemical Property:

Vapor Pressure:8.79E-06mmHg at 25°C
Boiling Point:363.2°Cat760mmHg
Flash Point:173.4°C
PSA：46.25000
Density:g/cm³
LogP:4.51550
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:255.1389920
Heavy Atom Count:17
Complexity:203

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1CCC(CC1)C2=CC=C(C=C2)O)N.Cl

Technology Process of (E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride

There total 3 articles about (E)-4-(4-(1-Aminoethyl)cyclohexyl)phenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 21060-31-1
trans-1-(4-Phenylcyclohexyl)-1-ethanon

: 113524-39-3
trans-1-<4-(4-idrossifenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / 90percent nitric acid / CHCl₃ / 1.5 h / -30 °C

2: 80 percent / hydrogen / 10percent Pd/C / ethyl acetate / Ambient temperature

3: 1.) 25percent sulfuric acid, sodium nitrite; 2.) conc. sulfuric acid / 1.) water, 0 deg C, 30 min; 2.) 1 h, r.t; 2 h, 70 deg C

4: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; sulfuric acid; hydrogen; nitric acid; sodium nitrite; palladium on activated charcoal; In chloroform; ethyl acetate;

Reference yield:

: 113524-41-7
trans-1-acetil-4-(4-nitrofenil)cicloesano

: 113524-39-3
trans-1-<4-(4-idrossifenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / hydrogen / 10percent Pd/C / ethyl acetate / Ambient temperature

2: 1.) 25percent sulfuric acid, sodium nitrite; 2.) conc. sulfuric acid / 1.) water, 0 deg C, 30 min; 2.) 1 h, r.t; 2 h, 70 deg C

3: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; sulfuric acid; hydrogen; sodium nitrite; palladium on activated charcoal; In ethyl acetate;

Reference yield:

: 113524-43-9
trans-1-acetil-4-(4-amminofenil)cicloesano

: 113524-39-3
trans-1-<4-(4-idrossifenil)cicloesil>etilammina cloridrato

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) 25percent sulfuric acid, sodium nitrite; 2.) conc. sulfuric acid / 1.) water, 0 deg C, 30 min; 2.) 1 h, r.t; 2 h, 70 deg C

2: 1.) 99percent formic acid; 2.) conc. hydrochloric acid / 1.) formamide, 180 deg C, 20 h; 2.) 5 h, reflux

With hydrogenchloride; formic acid; sulfuric acid; sodium nitrite;