Technology Process of Benzaldehyde, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]butoxy]-
There total 1 articles about Benzaldehyde, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]butoxy]- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: tetrahydrofuran / 0.75 h / -70 - 20 °C
2: 46.0 g / p-dimethylaminopyridine / CH2Cl2 / 3.5 h / 20 °C
3: 77 percent / HF; pyridine / 4 h / 20 °C
4: 74 percent / Dess-Martin periodinane; pyridine / CH2Cl2 / 3 h / 4 - 20 °C
5: K2CO3 / dimethylformamide / 5 h / 20 °C
6: dimethylformamide / 17 h / 20 °C
7: 61 percent / C39H32OP2 bis-phosphine; [(η3-allyl)PdCl]2 / tetrahydrofuran; dimethylformamide / 1 h / 20 °C
8: 57 percent / bis(2-methoxyethyl)aminosulfur trifluoride / CH2Cl2 / 3 h / -20 °C
With
pyridine; dmap; bis(η3-allyl-μ-chloropalladium(II)); C39H32OP2 bis-phosphine; hydrogen fluoride; potassium carbonate; Dess-Martin periodane; (bis-(2-methoxyethyl)amino)sulfur trufluoride;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tet.2003.04.008
- Guidance literature:
-
Multi-step reaction with 4 steps
1: tetrahydrofuran / 0.75 h / -70 - 20 °C
2: 46.0 g / p-dimethylaminopyridine / CH2Cl2 / 3.5 h / 20 °C
3: 77 percent / HF; pyridine / 4 h / 20 °C
4: 74 percent / Dess-Martin periodinane; pyridine / CH2Cl2 / 3 h / 4 - 20 °C
With
pyridine; dmap; hydrogen fluoride; Dess-Martin periodane;
In
tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tet.2003.04.008
