tert-Butyl(4-chlorobutoxy)dimethylsilane

Base Information

• Chemical Name: tert-Butyl(4-chlorobutoxy)dimethylsilane
• CAS No.: 89031-83-4
• Molecular Formula: C10H23 Cl O Si
• Molecular Weight: 222.831
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID10391971
• Nikkaji Number: J428.950A
• Mol file: 89031-83-4.mol

Synonyms:tert-Butyl(4-chlorobutoxy)dimethylsilane;89031-83-4;tert-butyl-(4-chlorobutoxy)-dimethylsilane;Silane, (4-chlorobutoxy)(1,1-dimethylethyl)dimethyl-;Silane,(4-chlorobutoxy)(1,1-dimethylethyl)dimethyl-;SCHEMBL3596460;DTXSID10391971;MTQPZXNVDIKRAK-UHFFFAOYSA-N;(4-chlorobutoxy)-t-butyldimethylsilane;4-chlorobutyl t-butyldimethylsilyl ether;(4-chlorobutoxy)-tert-butyldimethylsilane;tert.-butyl-(4-chlorobutoxy)dimethylsilane;1-Chloro-4-(tert-butyldimethylsiloxy)butane;CS-0006966;FT-0741490;tert-butyl-(4-chloro-butoxy)-dimethyl-silane;tert-Butyl(4-chlorobutoxy)dimethylsilane, 98%;(4-chlorobutoxy)(1,1-dimethylethyl)dimethyl-Silane

Chemical Property of tert-Butyl(4-chlorobutoxy)dimethylsilane

Chemical Property:

• Vapor Pressure: 0.0826mmHg at 25°C
• Refractive Index: n20/D 1.439(lit.)
• Boiling Point: 201 °C(lit.)
• Flash Point: 179 °F
• PSA: 9.23000
• Density: 0.87 g/mL at 25 °C(lit.)
• LogP: 4.02720
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 222.1206696
• Heavy Atom Count: 13
• Complexity: 140

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl(4-chlorobutoxy)dimethylsilane 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OCCCCCl

Technology Process of tert-Butyl(4-chlorobutoxy)dimethylsilane

There total 4 articles about tert-Butyl(4-chlorobutoxy)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-Chloro-1-butanol (928-51-8) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-(t-butyldimethylsiloxy)-1-chlorobutane (89031-83-4)

Guidance literature:

4-Chloro-1-butanol; tert-butyldimethylsilyl chloride; In dichloromethane; at 0 ℃; for 0.5h; Inert atmosphere;

With 1H-imidazole; In dichloromethane; at 0 ℃; for 1.5h; Inert atmosphere;

Reference yield: 91.0%

4-tert-butyldimethylsilyloxybutan-1-ol (87184-99-4) → 4-(t-butyldimethylsiloxy)-1-chlorobutane (89031-83-4)

Guidance literature:

With (chloro-phenylthio-methylene)dimethylammonium chloride; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/S0040-4039(00)00940-0

Reference yield:

1H-imidazole (288-32-4) + 4-Chloro-1-butanol (928-51-8) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-(t-butyldimethylsiloxy)-1-chlorobutane (89031-83-4)

Guidance literature:

In dichloromethane;

upstream raw materials:

4-Chloro-1-butanol

tert-butyldimethylsilyl chloride

t-butyldimethylsiyl triflate

4-tert-butyldimethylsilyloxybutan-1-ol

Downstream raw materials:

2-benzyloxymethoxymethyl-3-(4-dimethyl-t-butylsilyloxybutyl)cyclohex-2-enon

2-Bromo-3-<6-<(tert-butyldimethylsilyl)oxy>-1-hexylidene>-1-cyclohexene

3-[4-(tert-butyl-dimethyl-silanyloxy)-butoxy]-benzaldehyde

carbonic acid tert-butyl ester 1-{3-[4-(tert-butyl-dimethyl-silanyloxy)-butoxy]-phenyl}-allyl ester