2,5-Dimethylphenylhydroxylamine

Base Information

• Chemical Name: 2,5-Dimethylphenylhydroxylamine
• CAS No.: 3096-64-8
• Molecular Formula: C8H11 N O
• Molecular Weight: 137.181
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID10184946
• Mol file: 3096-64-8.mol

Synonyms:2,5-Dimethylphenylhydroxylamine;Hydroxylamine, N-(2,5-xylyl)-;3096-64-8;CCRIS 5432;N-(2,5-Xylyl)hydroxylamine;BRN 2638401;SCHEMBL10882869;DTXSID10184946

Chemical Property of 2,5-Dimethylphenylhydroxylamine

Chemical Property:

• Vapor Pressure: 0.0254mmHg at 25°C
• Boiling Point: 236.9°Cat760mmHg
• Flash Point: 106.1°C
• PSA: 32.26000
• Density: 1.12g/cm³
• LogP: 2.17750
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 137.084063974
• Heavy Atom Count: 10
• Complexity: 105

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C)NO

Technology Process of 2,5-Dimethylphenylhydroxylamine

There total 2 articles about 2,5-Dimethylphenylhydroxylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

mononitro-p-xylene (89-58-7) → N-(2,5-dimethylphenyl)hydroxylamine (3096-64-8)

Guidance literature:

With ammonium chloride; water; zinc; at 60 - 70 ℃;

Reference yield:

→ N-(2,5-dimethylphenyl)hydroxylamine (3096-64-8)

Guidance literature:

2,5-Dimethyl-nitrobenzol, Elektrol. Red. an der Hg-Kathode in 10percent A. enthaltender n/4 wss. H2SO4 bei -350 mV und 10grad;

Reference yield: 70.0%

N-(2,5-dimethylphenyl)hydroxylamine (3096-64-8) + benzoyl chloride (98-88-4) → N-(2,5-dimethylphenyl)-N-hydroxybenzamide

Guidance literature:

With sodium hydrogencarbonate; In diethyl ether; water; at 0 ℃; for 0.00277778h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.1c03779

upstream raw materials:

mononitro-p-xylene

Downstream raw materials:

bis-(2,5-dimethyl-phenyl)-diazene-N-oxide

4-methoxy-2,5-dimethylaniline

4-ethoxy-2,5-dimethyl-aniline

2,5-Dimethyl-1,4-benzoquinone