2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Base Information

Chemical Name:2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one
CAS No.:69429-59-0
Molecular Formula:C₁₅H₁₄O₃
Molecular Weight:242.274
Hs Code.:
DSSTox Substance ID:DTXSID90500281
Wikidata:Q82351750

Synonyms:2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one;69429-59-0;DTXSID90500281

Suppliers and Price of 2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:242.094294304
Heavy Atom Count:18
Complexity:271

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)C2=CC=CC=C2O)O

Technology Process of 2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

There total 5 articles about 2-Hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: rac-3'-phenyl-3H-spiro[benzo[b]furan-2,2'-oxiran]-3-one

: 4940-48-1,130609-35-7
rac-2-benzyl-2-hydroxy-2,3-dihydrobenzo[b]furan-3-one

: 69429-59-0,130609-34-6
rac-2-hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In toluene; at -25 - -20 ℃; for 2.5h;
DOI:10.1002/hlca.200490232

Reference yield:

: 7169-34-8
3-oxo-2,3-dihydrobenzo[b]furan

: 69429-59-0,130609-34-6
rac-2-hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Al₂O₃ / CH₂Cl₂ / 6 h / 20 °C

2: 35 percent / H₂O₂; benzyltrimethylammonium hydroxide / dioxane; methanol; H₂O / 0.67 h / 20 °C

3: 30 percent / H₂ / Pd/C / toluene / 20 °C

With aluminum oxide; hydrogen; dihydrogen peroxide; N-benzyl-trimethylammonium hydroxide; palladium on activated charcoal; In 1,4-dioxane; methanol; dichloromethane; water; toluene;
DOI:10.1002/hlca.200490232

Reference yield:

: 100-52-7
benzaldehyde

: 69429-59-0,130609-34-6
rac-2-hydroxy-1-(2-hydroxyphenyl)-3-phenylpropan-1-one

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / Al₂O₃ / CH₂Cl₂ / 6 h / 20 °C

2: 35 percent / H₂O₂; benzyltrimethylammonium hydroxide / dioxane; methanol; H₂O / 0.67 h / 20 °C

3: 30 percent / H₂ / Pd/C / toluene / 20 °C

With aluminum oxide; hydrogen; dihydrogen peroxide; N-benzyl-trimethylammonium hydroxide; palladium on activated charcoal; In 1,4-dioxane; methanol; dichloromethane; water; toluene;
DOI:10.1002/hlca.200490232